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Genmab — November 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • A Offline
    A Offline
    AaBforever
    wrote on sidst redigeret af
    #2921

    Nettosalg A/B i dag 36600

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    • StockBullS Offline
      StockBullS Offline
      StockBull
      wrote on sidst redigeret af
      #2922

      Lyder ikke af meget. Utroligt at det kan drive kursen 40 kr ned - men så kan den vel stige ligeså hurtigt

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      • A Offline
        A Offline
        AaBforever
        wrote on sidst redigeret af
        #2923

        Jeps..som sagt før, det beviser bare at A/B (hedgefonde) styrer hele butikken. Ikke bare i Genmab men i mange andre gode solide danske selskaber.

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #2924

          Men positivt at Nordea startede som nettosælger ( ca 3000 stk) og nu er kommet på købssiden med 3400 stk netto 🙂

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          • B Offline
            B Offline
            bibob
            wrote on sidst redigeret af
            #2925

            Kunne måske blive en interessant lukkeauktion. 😉

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            • A Offline
              A Offline
              AaBforever
              wrote on sidst redigeret af
              #2926

              A/B nettosalg 46600

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              • O Offline
                O Offline
                OHW
                wrote on sidst redigeret af
                #2927

                Måske er det JJ der sælger ud?

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                • O Offline
                  O Offline
                  OHW
                  wrote on sidst redigeret af
                  #2928

                  Undskyld, fejlpost!

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #2929

                    Interview Usmani: https://www.healio.com/hematology-oncology/education-lab/2017/03_march/multiple-myeloma-central/interview-spotlight-3-saad-z-usmani-md-facp

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #2930

                      "In 2017, the standard of care for myeloma is a three-drug combination. The debate about three drugs vs. two drugs is over based on available data."

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #2931

                        on Castor / Pollux : "...now have solid data in that regard. We have not seen these kinds of hazard ratios in myeloma clinical trials ever"

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                        • P Offline
                          P Offline
                          Plimsoller
                          wrote on sidst redigeret af
                          #2932

                          Thanks E L. Assume that is good news, but what is meant by "Hazard ratios", and dows that mean the "two drug combination" has won ?

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                          • P Offline
                            P Offline
                            Plimsoller
                            wrote on sidst redigeret af
                            #2933

                            dows = does

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                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #2934

                              No, that means that 3 drugs has won. The three drug combination is more effektive as I understand the article.

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #2935

                                yes, 3 wins. A hazard ratio (HR) is a calculation of the ratio of the chance of something harmful happening (such as
                                death or cancer recurrence) in one entire treatment group, divided by the risk of the event in the comparison
                                treatment group. A HR of 1 means there is no dierence between the groups, a HR of 2 is double the risk and a HR of 0.5 is
                                half the risk.

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                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #2936

                                  Så med andre ord har man aldrig før set så klare forbedringer

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #2937

                                    save this on your PC
                                    https://moodle2.units.it/pluginfile.php/146715/mod_resource/content/1/understanding_clinical_trials.pdf

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                                    • P Offline
                                      P Offline
                                      Plimsoller
                                      wrote on sidst redigeret af
                                      #2938

                                      Done. Thank you.

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                                      • G Offline
                                        G Offline
                                        gentogen
                                        wrote on sidst redigeret af
                                        #2939

                                        Læg også mærke til, at data er endnu bedre i nyeste abstract. Usmani henviser til en tidligere forbedring fra 43% CR til 46% CR. Den er nu 51% CR. Dara virker bedre og bedre med tiden. Og i øvrigt var allerede de 43% en sensation.

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #2940

                                          Ja også derfor det bliver spændende med Alcyone data - måske i morgen og ellers først på ASH

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