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Genmab — November 2017

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #2924

    Men positivt at Nordea startede som nettosælger ( ca 3000 stk) og nu er kommet på købssiden med 3400 stk netto 🙂

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    • B Offline
      B Offline
      bibob
      wrote on sidst redigeret af
      #2925

      Kunne måske blive en interessant lukkeauktion. 😉

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      • A Offline
        A Offline
        AaBforever
        wrote on sidst redigeret af
        #2926

        A/B nettosalg 46600

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        • O Offline
          O Offline
          OHW
          wrote on sidst redigeret af
          #2927

          Måske er det JJ der sælger ud?

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          • O Offline
            O Offline
            OHW
            wrote on sidst redigeret af
            #2928

            Undskyld, fejlpost!

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #2929

              Interview Usmani: https://www.healio.com/hematology-oncology/education-lab/2017/03_march/multiple-myeloma-central/interview-spotlight-3-saad-z-usmani-md-facp

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #2930

                "In 2017, the standard of care for myeloma is a three-drug combination. The debate about three drugs vs. two drugs is over based on available data."

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #2931

                  on Castor / Pollux : "...now have solid data in that regard. We have not seen these kinds of hazard ratios in myeloma clinical trials ever"

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                  • P Offline
                    P Offline
                    Plimsoller
                    wrote on sidst redigeret af
                    #2932

                    Thanks E L. Assume that is good news, but what is meant by "Hazard ratios", and dows that mean the "two drug combination" has won ?

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                    • P Offline
                      P Offline
                      Plimsoller
                      wrote on sidst redigeret af
                      #2933

                      dows = does

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                      • B Offline
                        B Offline
                        bibob
                        wrote on sidst redigeret af
                        #2934

                        No, that means that 3 drugs has won. The three drug combination is more effektive as I understand the article.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #2935

                          yes, 3 wins. A hazard ratio (HR) is a calculation of the ratio of the chance of something harmful happening (such as
                          death or cancer recurrence) in one entire treatment group, divided by the risk of the event in the comparison
                          treatment group. A HR of 1 means there is no dierence between the groups, a HR of 2 is double the risk and a HR of 0.5 is
                          half the risk.

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                          • G Offline
                            G Offline
                            gentogen
                            wrote on sidst redigeret af
                            #2936

                            Så med andre ord har man aldrig før set så klare forbedringer

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #2937

                              save this on your PC
                              https://moodle2.units.it/pluginfile.php/146715/mod_resource/content/1/understanding_clinical_trials.pdf

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                              • P Offline
                                P Offline
                                Plimsoller
                                wrote on sidst redigeret af
                                #2938

                                Done. Thank you.

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                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #2939

                                  Læg også mærke til, at data er endnu bedre i nyeste abstract. Usmani henviser til en tidligere forbedring fra 43% CR til 46% CR. Den er nu 51% CR. Dara virker bedre og bedre med tiden. Og i øvrigt var allerede de 43% en sensation.

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #2940

                                    Ja også derfor det bliver spændende med Alcyone data - måske i morgen og ellers først på ASH

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #2941

                                      Alletiders hvis de var med i morgen.

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                                      • J Offline
                                        J Offline
                                        JohnW
                                        wrote on sidst redigeret af
                                        #2942

                                        Undskyld, hvad er det der sker i morgen?

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                                        • G Offline
                                          G Offline
                                          GeorgeBest
                                          wrote on sidst redigeret af
                                          #2943

                                          det meddeles hvad der kommer med på ASH some late-breaker. ALCYONE er en kandidat hertil.

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