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Genmab — November 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • P Offline
    P Offline
    Plimsoller
    wrote on sidst redigeret af
    #2932

    Thanks E L. Assume that is good news, but what is meant by "Hazard ratios", and dows that mean the "two drug combination" has won ?

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    • P Offline
      P Offline
      Plimsoller
      wrote on sidst redigeret af
      #2933

      dows = does

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      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #2934

        No, that means that 3 drugs has won. The three drug combination is more effektive as I understand the article.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #2935

          yes, 3 wins. A hazard ratio (HR) is a calculation of the ratio of the chance of something harmful happening (such as
          death or cancer recurrence) in one entire treatment group, divided by the risk of the event in the comparison
          treatment group. A HR of 1 means there is no dierence between the groups, a HR of 2 is double the risk and a HR of 0.5 is
          half the risk.

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #2936

            Så med andre ord har man aldrig før set så klare forbedringer

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #2937

              save this on your PC
              https://moodle2.units.it/pluginfile.php/146715/mod_resource/content/1/understanding_clinical_trials.pdf

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              • P Offline
                P Offline
                Plimsoller
                wrote on sidst redigeret af
                #2938

                Done. Thank you.

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                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #2939

                  Læg også mærke til, at data er endnu bedre i nyeste abstract. Usmani henviser til en tidligere forbedring fra 43% CR til 46% CR. Den er nu 51% CR. Dara virker bedre og bedre med tiden. Og i øvrigt var allerede de 43% en sensation.

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #2940

                    Ja også derfor det bliver spændende med Alcyone data - måske i morgen og ellers først på ASH

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                    • B Offline
                      B Offline
                      bibob
                      wrote on sidst redigeret af
                      #2941

                      Alletiders hvis de var med i morgen.

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                      • J Offline
                        J Offline
                        JohnW
                        wrote on sidst redigeret af
                        #2942

                        Undskyld, hvad er det der sker i morgen?

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                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #2943

                          det meddeles hvad der kommer med på ASH some late-breaker. ALCYONE er en kandidat hertil.

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #2944

                            Hvis ikke ALCYONE får late-breaker status, vil markedet nok tolke det som negativt. Er der mon lækket noget i dag. Genmab er ned, og markedet er op?

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                            • J Offline
                              J Offline
                              JohnW
                              wrote on sidst redigeret af
                              #2945

                              Så vi får at vide om ALCYONE kommer med eller ej, men vi får vel ikke nogle resultater af ALCYONE i morgen?

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                              • J Offline
                                J Offline
                                JohnW
                                wrote on sidst redigeret af
                                #2946

                                Ok. I see. Så bliver morgendagen jo spændende.

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                                • P Offline
                                  P Offline
                                  polle1
                                  wrote on sidst redigeret af
                                  #2947

                                  Kommer disse late breaker som en samlet meddelelse, og hvad tid på dagen ?

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #2948

                                    Alle 6 mulige abstracts bliver offentliggjort på en gang. Hele abstractet med alle væsentlige data kommer ud. Vel omkring kl. 14 når de står op derovre.

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                                    • J Offline
                                      J Offline
                                      JohnW
                                      wrote on sidst redigeret af
                                      #2949

                                      Hvis ALCYONE ikke kommer med som late breaker, hvornår får vi så data fra ALCYONE at se?

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                                      • P Offline
                                        P Offline
                                        polle1
                                        wrote on sidst redigeret af
                                        #2950

                                        Mange tak for info, Bulder !

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                                        • G Offline
                                          G Offline
                                          GeorgeBest
                                          wrote on sidst redigeret af
                                          #2951

                                          Sukkeralf mener de alligevel kommer på ASH, men pakket ind i en anden præsentation, evt. CASTOR eller POLLUX

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