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  4. Genmab — November 2023

Genmab — November 2023

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #1471

    Spændende med deres trispecifikke antistof JNJ-79635322 - en mulig arvtager til Tec+Tal. Mon det er deres egen teknologi?

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    0
    • StockBullS Offline
      StockBullS Offline
      StockBull
      wrote on sidst redigeret af
      #1472

      Yes correct EL. GDP for Q3 was very high but many CEO guided lower earnings in Q4. Usually in high interest environment GDP drop with 2-3% per Q so maybe 2.5% in Q4 and -0.5% in Q1-2024. Time will show. So Q4 / annual reports and 2024 guiding for 2024 thats coming in January to February will be very interesting for the marked.

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      0
      • StockBullS Offline
        StockBullS Offline
        StockBull
        wrote on sidst redigeret af
        #1473

        Men ja, også muligt Joe Biden fortsætter med at stimulere økonomien med store summer og derved kan holde ernings oppe. Men så kommer renten jo ikke ned hvis økonomien er er i top og alle har jobs. Den høje rente vil bare gøre USAs gæld større og større og koste ca. 1.5T per år i renter. Det er jo fordi Biden stort set bare har fortsat covid stimulus at gælden vokser vildt og nu ikke kan tæmmes. Hele lokummet kan vælte som i 2009.

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        0
        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #1474

          Godmorgen 🙂

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          0
          • S Offline
            S Offline
            Stroka
            wrote on sidst redigeret af
            #1475

            God morgen. 🙂

            1 Reply Last reply
            0
            • B Offline
              B Offline
              bibob
              wrote on sidst redigeret af
              #1476

              Blenrep. https://firstwordpharma.com/story/5804061?from=article

              1 Reply Last reply
              0
              • B Offline
                B Offline
                bibob
                wrote on sidst redigeret af
                #1477

                Just a moment...

                favicon

                (firstwordpharma.com)

                1 Reply Last reply
                0
                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1478

                  nejm -Amivantamab plus Chemotherapy in NSCLC with EGFR Exon 20 Insertions
                  https://www.nejm.org/doi/full/10.1056/NEJMoa2306441

                  1 Reply Last reply
                  0
                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1479

                    on Blenrep i really need to see the data first; there is a chance some Dara refractory patients were included, which we know would disadvantage the Dara arm in the trial. Need to see if that is the case.

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                    0
                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1480

                      Otherwise it would possibly be more advantageous for Teclistamab then for Blenrep due to Blenrep toxicities.

                      1 Reply Last reply
                      0
                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1481

                        Also, JNJ have in trial Dara + Teclistamab, which will likely be even better then the Dream 7 combo

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                        0
                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #1482

                          In Majestec 1 tec+dara had 63% ORR and 39% CR in 4. Line. The ph 3 study is 2.-4. Line.

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                          0
                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #1483

                            Majestec 3 will probably read out in 2025.

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                            0
                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #1484

                              Just a moment...

                              favicon

                              (www.nejm.org)

                              1 Reply Last reply
                              0
                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #1485

                                Majestec1 was mono I believe, Majestec2 with Dara i think , has data already, need to look it up

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                                0
                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #1486

                                  Yes you are right. Majestec 1 was mono. In Majestec 2: the overall response rate (ORR) was 93.5 percent.1 Among all patients in the trial, VGPRs or better were achieved by 90.3 percent of patients, and 54.8 percent of patients achieved a complete response (CR) or better.

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                                  0
                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1487

                                    Site Maintenance

                                    favicon

                                    (www.jnj.com)

                                    1 Reply Last reply
                                    0
                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1488

                                      Majestec 2 also combined with lenalidimide. So DR+Tec.

                                      1 Reply Last reply
                                      0
                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1489

                                        Will be hard to beat for bela maf.

                                        1 Reply Last reply
                                        0
                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #1490

                                          I wonder why GSK didn’t combine bela maf with len.

                                          1 Reply Last reply
                                          0

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