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  4. Genmab — November 2023

Genmab — November 2023

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1480

    Otherwise it would possibly be more advantageous for Teclistamab then for Blenrep due to Blenrep toxicities.

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    0
    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1481

      Also, JNJ have in trial Dara + Teclistamab, which will likely be even better then the Dream 7 combo

      1 Reply Last reply
      0
      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #1482

        In Majestec 1 tec+dara had 63% ORR and 39% CR in 4. Line. The ph 3 study is 2.-4. Line.

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        0
        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #1483

          Majestec 3 will probably read out in 2025.

          1 Reply Last reply
          0
          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #1484

            Just a moment...

            favicon

            (www.nejm.org)

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            0
            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #1485

              Majestec1 was mono I believe, Majestec2 with Dara i think , has data already, need to look it up

              1 Reply Last reply
              0
              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1486

                Yes you are right. Majestec 1 was mono. In Majestec 2: the overall response rate (ORR) was 93.5 percent.1 Among all patients in the trial, VGPRs or better were achieved by 90.3 percent of patients, and 54.8 percent of patients achieved a complete response (CR) or better.

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #1487

                  Site Maintenance

                  favicon

                  (www.jnj.com)

                  1 Reply Last reply
                  0
                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #1488

                    Majestec 2 also combined with lenalidimide. So DR+Tec.

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                    0
                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #1489

                      Will be hard to beat for bela maf.

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                      0
                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #1490

                        I wonder why GSK didn’t combine bela maf with len.

                        1 Reply Last reply
                        0
                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #1491

                          i think they also have a Ph 1/2 with len. They have more trials , they "Dreamm"
                          a lot 😉

                          1 Reply Last reply
                          0
                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #1492

                            Tisotumab Vedotin Survival Data in Cervical Cancer Are “Game-Changing" https://www.cancernetwork.com/view/tisotumab-vedotin-survival-data-in-cervical-cancer-are-game-changing-

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #1493

                              Trial investigator Brian Slomovitz, MD, Director of Gynecologic Oncology and Co-Chair of the Cancer Research Committee at Mount Sinai Medical Center, discusses results from the global, randomized, open-label Phase 3 innovaTV 301 trial
                              https://www.youtube.com/watch?v=HIZzLVIh15c

                              1 Reply Last reply
                              0
                              • Don_JoningD Offline
                                Don_JoningD Offline
                                Don_Joning
                                wrote on sidst redigeret af
                                #1494

                                Det lyder umiddelbart rigtig godt med Tiso, det er en frygtelig sygdom!

                                1 Reply Last reply
                                0
                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #1495

                                  AbbVie will pay $31.26 per share in cash, or approximately $10.1 billion, to acquire ImmunoGen, gaining the antibody-drug conjugate Elahere (mirvetuximab soravtansine).

                                  1 Reply Last reply
                                  0
                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #1496

                                    https://finance.yahoo.com/news/abbvie-acquire-immunogen-including-flagship-123000719.html ligner +80-90% i præmium

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                                    0
                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #1497

                                      Ingen godkendte stoffer, men et på vej https://investor.immunogen.com/news-releases/news-release-details/immunogen-announces-european-medicines-agency-acceptance

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                                      0
                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #1498

                                        I wished you would have told me this yesterday 😉

                                        1 Reply Last reply
                                        0
                                        • K Offline
                                          K Offline
                                          Klarussen
                                          wrote on sidst redigeret af
                                          #1499

                                          Like the lotto numbers 😉

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                                          0

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