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  4. Genmab — November 2023

Genmab — November 2023

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1466

    New trial: Safety and Preliminary Efficacy of BNT314 With or Without an Immune Checkpoint Inhibitor in Cancer Patients With Malignant Solid Tumors https://clinicaltrials.gov/study/NCT06150183 (GEN1059 = BNT314

    DuoBody-EpCAMx4-1BB
    )

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #1467

      https://www.janssen.com/johnson-johnson-highlights-its-preeminent-leadership-hematology-through-differentiated-blood-cancer

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      0
      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #1468

        Janssen ASH

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        • P Offline
          P Offline
          Pensionisten
          wrote on sidst redigeret af
          #1469

          Det var da godt nok noget af en smøre, @Sukkeralf. Og hvis de så kunne starte med at oplyse, at Genmab har vundet ankesagen - så kunne det jo blive ligefremt dejligt 😄

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #1470

            Ja de fylder godt - mangler lige epcoritamab

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #1471

              Spændende med deres trispecifikke antistof JNJ-79635322 - en mulig arvtager til Tec+Tal. Mon det er deres egen teknologi?

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              • StockBullS Offline
                StockBullS Offline
                StockBull
                wrote on sidst redigeret af
                #1472

                Yes correct EL. GDP for Q3 was very high but many CEO guided lower earnings in Q4. Usually in high interest environment GDP drop with 2-3% per Q so maybe 2.5% in Q4 and -0.5% in Q1-2024. Time will show. So Q4 / annual reports and 2024 guiding for 2024 thats coming in January to February will be very interesting for the marked.

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                • StockBullS Offline
                  StockBullS Offline
                  StockBull
                  wrote on sidst redigeret af
                  #1473

                  Men ja, også muligt Joe Biden fortsætter med at stimulere økonomien med store summer og derved kan holde ernings oppe. Men så kommer renten jo ikke ned hvis økonomien er er i top og alle har jobs. Den høje rente vil bare gøre USAs gæld større og større og koste ca. 1.5T per år i renter. Det er jo fordi Biden stort set bare har fortsat covid stimulus at gælden vokser vildt og nu ikke kan tæmmes. Hele lokummet kan vælte som i 2009.

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                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #1474

                    Godmorgen 🙂

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                    0
                    • S Offline
                      S Offline
                      Stroka
                      wrote on sidst redigeret af
                      #1475

                      God morgen. 🙂

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                      • B Offline
                        B Offline
                        bibob
                        wrote on sidst redigeret af
                        #1476

                        Blenrep. https://firstwordpharma.com/story/5804061?from=article

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                        • B Offline
                          B Offline
                          bibob
                          wrote on sidst redigeret af
                          #1477

                          Just a moment...

                          favicon

                          (firstwordpharma.com)

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                          0
                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #1478

                            nejm -Amivantamab plus Chemotherapy in NSCLC with EGFR Exon 20 Insertions
                            https://www.nejm.org/doi/full/10.1056/NEJMoa2306441

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #1479

                              on Blenrep i really need to see the data first; there is a chance some Dara refractory patients were included, which we know would disadvantage the Dara arm in the trial. Need to see if that is the case.

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #1480

                                Otherwise it would possibly be more advantageous for Teclistamab then for Blenrep due to Blenrep toxicities.

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #1481

                                  Also, JNJ have in trial Dara + Teclistamab, which will likely be even better then the Dream 7 combo

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1482

                                    In Majestec 1 tec+dara had 63% ORR and 39% CR in 4. Line. The ph 3 study is 2.-4. Line.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1483

                                      Majestec 3 will probably read out in 2025.

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                                      0
                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1484

                                        Just a moment...

                                        favicon

                                        (www.nejm.org)

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #1485

                                          Majestec1 was mono I believe, Majestec2 with Dara i think , has data already, need to look it up

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                                          0

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