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  4. Genmab — Marts 2022

Genmab — Marts 2022

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #530

    Børsen summary in Medwatch lol https://medwatch.dk/Medicinal___Biotek/article13878824.ece

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #531

      Ja og problemet er trods alt, at det skal først skal kæmpe med Darzalex off patent og senere Darzalex faspro, så man skal godt nok være god. Chancerne er nok størst hvis det virker i nye indikationer eller i patienter der ikke længere responderer på daratumumab.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #532

        development from other companies will make competition to Dara stronger and stronger; JNJ will have to keep improving as well . If Hexa is clearly better I find it hard to believe JNJ would not develop it further

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #533

          I would like to know more about the UBS Hex38
          comments

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #534

            EL i would like that too - but is it realistic to expect HexaCD38 to be clearly better than daratumumab. I´m not so sure - so far vi have not seen that many proofs about the hexabody platform in the clinic or interest from partners

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #535

              Vi ved at carvykti er super dyr og besværlig at arbejde med. Økonomisk får JNJ også mindre ud af den aftale end daraaftalen. Så hvis hexa38 kan komme på højde med det stof i effekt og bivirkninger er der ikke noget der taler for, at de ikke hopper på hexa38.

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              • B Offline
                B Offline
                bibob
                wrote on sidst redigeret af
                #536

                De kunne vel i princippet lave aftaler på begge stoffer. ??

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #537

                  Men det er så også noget af en ambition for hex38. ORR på 98%, 78% sCR i 7. linje!

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #538

                    @Sukkeralf I was hoping for another hexabody mention in the BionTech presentation but there was none this time. The start of a hexabody trail with them would be nice support for the platform

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                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #539

                      Yes Jan has promissed us that so hopefully its only a few months away

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #540

                        But still thats not clinical data and we dont now if its a new or old target

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #541

                          It was Momenta Pharmaceuticals Janssen bought:

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #542

                            Link Preview Image
                            Post Page

                            Authentic, fact-based healthcare content writing services.

                            favicon

                            (bareskymarketing.com)

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #543

                              M267: a SIFbody candidate targeting CD38

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #544

                                SIFbody er åbenbart noget hexabody-agtigt, (multimerization). Mere potent end dara. Bedre til at aktivere CDC. Så en direkte konkurrent til superdara. https://aacrjournals.org/cancerres/article/79/13_Supplement/561/637257/Abstract-561-Discovery-of-a-potential-best-in

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #545

                                  En 3 år gammel poster. Hvor står M267 i dag ?

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #546

                                    Jeg kan ikke finde noget på stoffet efter medio 2020.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #547

                                      Kan være den lider samme skæbne som tak-079 tilsyneladende har lidt. Ser ikke ud til den er i klinikken.

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                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #548

                                        Lad os håbe det

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                                        • P Offline
                                          P Offline
                                          ProinvestorNEWS
                                          wrote on sidst redigeret af
                                          #549

                                          Er bunden i biotech fundet? Store ændringer i Zealand Pharma. Efter generalforsamlingen i Genmab. Carlsberg går ud af Rusland. Input til olieaktier i debatten på ProInvestor.com. Det er nogle af overskifterne i ugens korte kommentar fra Helge Larsen. https://www.proinvestor.com/boards/102583

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