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  4. Genmab — Marts 2022

Genmab — Marts 2022

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #533

    I would like to know more about the UBS Hex38
    comments

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #534

      EL i would like that too - but is it realistic to expect HexaCD38 to be clearly better than daratumumab. I´m not so sure - so far vi have not seen that many proofs about the hexabody platform in the clinic or interest from partners

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      • SolsenS Offline
        SolsenS Offline
        Solsen
        wrote on sidst redigeret af
        #535

        Vi ved at carvykti er super dyr og besværlig at arbejde med. Økonomisk får JNJ også mindre ud af den aftale end daraaftalen. Så hvis hexa38 kan komme på højde med det stof i effekt og bivirkninger er der ikke noget der taler for, at de ikke hopper på hexa38.

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #536

          De kunne vel i princippet lave aftaler på begge stoffer. ??

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #537

            Men det er så også noget af en ambition for hex38. ORR på 98%, 78% sCR i 7. linje!

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #538

              @Sukkeralf I was hoping for another hexabody mention in the BionTech presentation but there was none this time. The start of a hexabody trail with them would be nice support for the platform

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #539

                Yes Jan has promissed us that so hopefully its only a few months away

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #540

                  But still thats not clinical data and we dont now if its a new or old target

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #541

                    It was Momenta Pharmaceuticals Janssen bought:

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                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #542

                      Link Preview Image
                      Post Page

                      Authentic, fact-based healthcare content writing services.

                      favicon

                      (bareskymarketing.com)

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #543

                        M267: a SIFbody candidate targeting CD38

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #544

                          SIFbody er åbenbart noget hexabody-agtigt, (multimerization). Mere potent end dara. Bedre til at aktivere CDC. Så en direkte konkurrent til superdara. https://aacrjournals.org/cancerres/article/79/13_Supplement/561/637257/Abstract-561-Discovery-of-a-potential-best-in

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #545

                            En 3 år gammel poster. Hvor står M267 i dag ?

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #546

                              Jeg kan ikke finde noget på stoffet efter medio 2020.

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #547

                                Kan være den lider samme skæbne som tak-079 tilsyneladende har lidt. Ser ikke ud til den er i klinikken.

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #548

                                  Lad os håbe det

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                                  0
                                  • P Offline
                                    P Offline
                                    ProinvestorNEWS
                                    wrote on sidst redigeret af
                                    #549

                                    Er bunden i biotech fundet? Store ændringer i Zealand Pharma. Efter generalforsamlingen i Genmab. Carlsberg går ud af Rusland. Input til olieaktier i debatten på ProInvestor.com. Det er nogle af overskifterne i ugens korte kommentar fra Helge Larsen. https://www.proinvestor.com/boards/102583

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                                    • P Offline
                                      P Offline
                                      ProinvestorNEWS
                                      wrote on sidst redigeret af
                                      #550

                                      Torsdagens aktier: Defensive aktier holdt stand i rødt marked https://proinvestor.com/investornyt/803041/torsdagens-aktier-defensive-aktier-holdt-stand-i-rodt-marked

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #551

                                        JW ynder at sammenligne Genmab med Regeneron. ATH for sidstnævnte i dag https://finance.yahoo.com/quote/REGN?p=REGN&.tsrc=fin-notif - om et par år måske 🙂

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #552

                                          Genmab would need around dkk7850 to get to a similar market cap. yeah, a few years sounds about right 😉

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