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Genmab — Februar 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #379

    But solids will be followed with sc dara and patent protection will be around 2033-2035 so they could get on the marked for some years at least

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #380

      But again solids are dead according to Jan

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #381

        ok, clear. yes, i know Jan said that. At the same time i feel we never got a very good explanation of what really were the issues in those trials; it left me feeling that possibly with other combinations results could be different. But probably pure fiction pure fiction in my head...

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        • JørgenVarnæsJ Offline
          JørgenVarnæsJ Offline
          JørgenVarnæs
          wrote on sidst redigeret af
          #382

          JV on things that are dead. Especially dara in solids: https://www.youtube.com/watch?v=yR5Z4n1TdSI

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #383

            E L on the other hand we only have preclinical work that says it might work ! Jan has promissed us data from the Carina study that never came and also data from solid study and we have never seen that either. When things goes wrong people are usually not that keen on presenting

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #384

              yes, very true…

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #385

                Studies in dara-nivo in solids will read out this year. You never know.

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #386

                  But did BMs stop the dara arm in these trials ?

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #387

                    They stopped recruiting prematurely in one of them. We haven't heard of anything in the two others.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #388

                      No, you are right. Enrollment was stopped in the dara-arm in Checkmate358.

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #389

                        Checkmate142 is not recruiting in general. But the dara-arm has not been specifically changed.

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                        • B Offline
                          B Offline
                          bibob
                          wrote on sidst redigeret af
                          #390

                          Ninlaro bliver ikke godkendt til vedligeholdelse. https://medwatch.dk/Medicinal___Biotek/article11168756.ece?utm_campaign=MedWatch Middag&utm_content=2019-02-06_B&utm_medium=email&utm_source=medwatch

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                          • R Offline
                            R Offline
                            Relax
                            wrote on sidst redigeret af
                            #391

                            Tak for svar angående mit spørgsmål om dividende og opkøbsprogram. Er enig at investeringer i egen pipeline er det bedste for aktionærerne. På den anden side er tre år med stagnerende/negativt afkast, en negativt vurderet pipeline (min menning) og et dyrt warrants program, ikke det bedste for aktionærerne. Tænkte derfor at Genmab bliver nød til at komme med andent end eventuelle blockbustere engang i fremtiden.

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #392

                              for the library: Mechanism of Action and Novel IMiD-Based Compounds
                              and Combinations in Multiple Myeloma https://sci-hub.tw/10.1097/ppo.0000000000000354

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #393

                                Are 4-Drug Regimens Here to Stay? Role in Induction
                                and Salvage Therapies https://sci-hub.tw/10.1097/ppo.0000000000000351

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #394

                                  Here to stay? Yes, but who shall pay?

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #395

                                    😉

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #396

                                      Now we are at it. We haven't heard of any submission for approval of Cassiopeia-regimen. D-VTd. 3½ months since we saw top line.

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                                      • P Offline
                                        P Offline
                                        peter12
                                        wrote on sidst redigeret af
                                        #397

                                        Har du et kvalificeret gæt ?

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #398

                                          I forbindelse med patentsnakken for lidt siden: Ser lige at Celgene også har patent på Thalidomid, som udløber i 2023 i US og 2019 i Europa. Det kan jo undre, da Thalidomid er et tudsegammelt oprindeligt tysk stof. Hvem husker ikke skandalen i 50'erne. Men Celgene har åbenbart lavet en så anderledes ny formulering, at de har kunnet opnå ny patent. https://www.sec.gov/Archives/edgar/data/816284/000095012310055985/filename1.htm

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