Genmab — Marts 2021
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EL they should have a VERY god picture of that already when they compare thier preclinical PK models
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Bulder: har vi set noget konkret på om Roche vil udvikle en subcu version for Glofitamab?
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Ja: Robust development programmes are ongoing for mosunetuzumab and glofitamab, investigating the treatments as monotherapies and in combination with other molecules, as well as more convenient forms of administration such as subcutaneous administration, with several phase III trials planned in the near future.https://www.roche.com/media/releases/med-cor-2020-12-08.htm
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We always need human trials. But its to closly related molecules, so there is a lot that can be compared in preclinical models vs dara clinical data
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two closely....
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14:13 @Bulder: men referencen til subcu kan jo være relateret til Mosunetuzumab, hvor vi har vist siden sidste efterår at Roche vil udvikle en subcu version
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New smal trial - An Open Label Study to Evaluate Daratumumab in Participants With Moderate to Severe Systemic Lupus Erythematosus (DARALUP) https://clinicaltrials.gov/ct2/show/NCT04810754?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody+OR+hexabody+OR+Teclistamab+OR+Amivantamab+OR+Talquetamab+OR+Epcoritamab+OR+DuoHexabody&lupd_s=03%2F23%2F2021&draw=2&rank=1
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Q&A starter kl. 15,30.
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