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Genmab — Marts 2021

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #1100

    Ja: Robust development programmes are ongoing for mosunetuzumab and glofitamab, investigating the treatments as monotherapies and in combination with other molecules, as well as more convenient forms of administration such as subcutaneous administration, with several phase III trials planned in the near future.https://www.roche.com/media/releases/med-cor-2020-12-08.htm

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #1101

      Men epco kan jo komme først som sc.

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      0
      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1102

        troldmanden are you essentially saying they can estimate toxicity already in those preclinical models? (i can understand efficacy, but thought you would need it in human to find out how toxic it is?)

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        • troldmandenT Offline
          troldmandenT Offline
          troldmanden
          wrote on sidst redigeret af
          #1103

          We always need human trials. But its to closly related molecules, so there is a lot that can be compared in preclinical models vs dara clinical data

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          • troldmandenT Offline
            troldmandenT Offline
            troldmanden
            wrote on sidst redigeret af
            #1104

            two closely....

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #1105

              14:13 @Bulder: men referencen til subcu kan jo være relateret til Mosunetuzumab, hvor vi har vist siden sidste efterår at Roche vil udvikle en subcu version

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1106

                Det kan være. Jeg ved ikke specifikt om glofi.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1107

                  New smal trial - An Open Label Study to Evaluate Daratumumab in Participants With Moderate to Severe Systemic Lupus Erythematosus (DARALUP) https://clinicaltrials.gov/ct2/show/NCT04810754?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody+OR+hexabody+OR+Teclistamab+OR+Amivantamab+OR+Talquetamab+OR+Epcoritamab+OR+DuoHexabody&lupd_s=03%2F23%2F2021&draw=2&rank=1

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1108

                    we had a few articles indicating Dara would work here and in september an article where this Berlin hospital announced they would start a trial

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                    0
                    • Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktør
                      wrote on sidst redigeret af
                      #1109

                      Q&A starter kl. 15,30. 🙂

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                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #1110

                        SLE er en oplagt indikation for dara, som man ikke forstår hvorfor JNJ ikke har angrebet.

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                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #1111

                          NBI nede med 2,5% og Genmab kun 1% ... positivt 😉

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                          0
                          • S Offline
                            S Offline
                            svak
                            wrote on sidst redigeret af
                            #1112

                            Hvor følger vi o&a - der er ikke noget under fanen?

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                            • exitnuE Offline
                              exitnuE Offline
                              exitnu
                              wrote on sidst redigeret af
                              #1113

                              Her: https://www.proinvestor.com/chathistory/-133/qa-genmab-2021-03-23

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                              • S Offline
                                S Offline
                                svak
                                wrote on sidst redigeret af
                                #1114

                                tak -
                                exitnu

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #1115

                                  Hexa38 lyder super interessant på Q&A

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                                  0
                                  • P Offline
                                    P Offline
                                    peter12
                                    wrote on sidst redigeret af
                                    #1116

                                    Ja og han lyder optimistisk 😉

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                                    0
                                    • M Offline
                                      M Offline
                                      Mcjean
                                      wrote on sidst redigeret af
                                      #1117

                                      Yep det eneste tidspunkt han havde sin "det kører bare" hat på:-)

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #1118

                                        Jeg tvivler stærkt på at HALO skal involveres i hexacd38

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                                        0
                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #1119

                                          Hvad mon CT siger

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                                          0

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