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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • K Offline
    K Offline
    KWC
    wrote on sidst redigeret af
    #868

    Genmab Announces Data to be Presented at ASCO20 Virtual Scientific Program
    Media Release

    Copenhagen, Denmark, April 29, 2020

    Six industry sponsored abstracts regarding Genmab and Genmab partnered programs selected for presentation at ASCO20 Virtual Scientific Program, including data from the epcoritamab (DuoBody®-CD3xCD20) Ph I/II dose-escalation study.

    Genmab A/S (Nasdaq: GMAB) announced today that six industry sponsored abstracts regarding Genmab and Genmab partnered programs were accept

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    • K Offline
      K Offline
      KWC
      wrote on sidst redigeret af
      #869

      accepted for presentation at the American Society of Clinical Oncology 2020 (ASCO20) Virtual Scientific Program, taking place from May 29 to 31, 2020. The titles of the abstracts are currently available on the ASCO Meeting Library, with the full abstracts scheduled to be published on May 13, 2020. A list of the abstracts is provided below, and includes one on epcoritamab, one on tisotumab vedotin (Trial in Progress) and four on daratumumab. Beginning Friday, May 29, 2020 at 8:00 AM EDT, poster s

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      • K Offline
        K Offline
        KWC
        wrote on sidst redigeret af
        #870

        “Although this year’s ASCO will be a virtual conference due to the difficult and unprecedented circumstances, we are pleased that data on our proprietary pipeline and partnered programs has been accepted for presentation at this prestigious conference. We are particularly looking forward to the data presentation that will demonstrate continued solid progress in our development of epcoritamab (DuoBody-CD3xCD20),” said Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab.

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        • G Offline
          G Offline
          GeorgeBest
          wrote on sidst redigeret af
          #871

          https://ir.genmab.com/news-releases/news-release-details/genmab-announces-data-be-presented-asco20-virtual-scientific

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          • K Offline
            K Offline
            KWC
            wrote on sidst redigeret af
            #872

            🙂

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            • K Offline
              K Offline
              KWC
              wrote on sidst redigeret af
              #873

              Epcoritamab:
              Epcoritamab (GEN3013; DuoBody-CD3×CD20) to induce complete response in patients with relapsed/ refractory B-NHL: Complete dose escalation data and efficacy results from a phase I/II trial - Virtual poster presentation

              Tisotumab Vedotin:
              Phase Ib/II trial of tisotumab vedotin ± bevacizumab, pembrolizumab, or carboplatin in recurrent or metastatic cervical cancer (innovaTV 205/ENGOT-cx8/GOG-3024) - Virtual poster presentation

              Daratumumab (Submitted by Janssen Biotech, Inc.):
              Cort

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              • K Offline
                K Offline
                KWC
                wrote on sidst redigeret af
                #874

                Corticosteroid Tapering in Patients with Relapsed or Refractory Multiple Myeloma Receiving Subcutaneous Daratumumab: Part 3 of the Open-label, Multicenter, Phase 1b PAVO Study - Virtual poster presentation

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #875

                  Hvorfor nævner de ikke Teclistamab og Amivantamab? Det er ellers de tunge MM-drenge (og piger) der er med i Teclistamab.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #876

                    Nu virker søgemaskinen. Fandt denne her: A phase Ib study of TAK-079, an investigational anti-CD38 monoclonal antibody (mAb) in patients with relapsed/ refractory multiple myeloma (RRMM): Preliminary results. Skal satme under observation.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #877

                      GSK's ADC er der også: DREAMM-2: Single-agent belantamab mafodotin (GSK2857916) in patients with relapsed/refractory multiple myeloma (RRMM) and high-risk (HR) cytogenetics.

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #878

                        Og i 1. linje: DREAMM-9: Phase III study of belantamab mafodotin plus VRd versus VRd alone in transplant-ineligible newly diagnosed multiple myeloma (TI NDMM).

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #879

                          Men dreamm-9 kan der umuligt være data fra. Det er nok bare en præsentation af studiet. Så sent som februar var dreamm-9 kun på planlægningsstadiet.

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #880

                            Mon ikke JNJ kunne vælge at holde lav profil mht kombinationsmulighederne til dara af konkurrencehensyn. De er i fuld gang med at afprøve https://clinicaltrials.gov/ct2/show/NCT04108195

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #881

                              Det kunne måske forklare Teclistamab, men ikke Amivantamab?

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                              • SolsenS Offline
                                SolsenS Offline
                                Solsen
                                wrote on sidst redigeret af
                                #882

                                BTD = late breaker

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #883

                                  ?

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #884

                                    Bulder 21:33. Er det ikke ligegyldigt om Genmab fremhæver disse? De er jo med på ASCO.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #885

                                      De plejer at opregne revl og krat

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                                      • G Offline
                                        G Offline
                                        GeorgeBest
                                        wrote on sidst redigeret af
                                        #886

                                        Ja rigtigt

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #887

                                          Men måske overlader de det til JnJ at reklamere

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