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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #867

    Yes, or maybe EHA, 2 weeks after asco

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    • K Offline
      K Offline
      KWC
      wrote on sidst redigeret af
      #868

      Genmab Announces Data to be Presented at ASCO20 Virtual Scientific Program
      Media Release

      Copenhagen, Denmark, April 29, 2020

      Six industry sponsored abstracts regarding Genmab and Genmab partnered programs selected for presentation at ASCO20 Virtual Scientific Program, including data from the epcoritamab (DuoBody®-CD3xCD20) Ph I/II dose-escalation study.

      Genmab A/S (Nasdaq: GMAB) announced today that six industry sponsored abstracts regarding Genmab and Genmab partnered programs were accept

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      • K Offline
        K Offline
        KWC
        wrote on sidst redigeret af
        #869

        accepted for presentation at the American Society of Clinical Oncology 2020 (ASCO20) Virtual Scientific Program, taking place from May 29 to 31, 2020. The titles of the abstracts are currently available on the ASCO Meeting Library, with the full abstracts scheduled to be published on May 13, 2020. A list of the abstracts is provided below, and includes one on epcoritamab, one on tisotumab vedotin (Trial in Progress) and four on daratumumab. Beginning Friday, May 29, 2020 at 8:00 AM EDT, poster s

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        • K Offline
          K Offline
          KWC
          wrote on sidst redigeret af
          #870

          “Although this year’s ASCO will be a virtual conference due to the difficult and unprecedented circumstances, we are pleased that data on our proprietary pipeline and partnered programs has been accepted for presentation at this prestigious conference. We are particularly looking forward to the data presentation that will demonstrate continued solid progress in our development of epcoritamab (DuoBody-CD3xCD20),” said Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab.

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          • G Offline
            G Offline
            GeorgeBest
            wrote on sidst redigeret af
            #871

            https://ir.genmab.com/news-releases/news-release-details/genmab-announces-data-be-presented-asco20-virtual-scientific

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            • K Offline
              K Offline
              KWC
              wrote on sidst redigeret af
              #872

              🙂

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              • K Offline
                K Offline
                KWC
                wrote on sidst redigeret af
                #873

                Epcoritamab:
                Epcoritamab (GEN3013; DuoBody-CD3×CD20) to induce complete response in patients with relapsed/ refractory B-NHL: Complete dose escalation data and efficacy results from a phase I/II trial - Virtual poster presentation

                Tisotumab Vedotin:
                Phase Ib/II trial of tisotumab vedotin ± bevacizumab, pembrolizumab, or carboplatin in recurrent or metastatic cervical cancer (innovaTV 205/ENGOT-cx8/GOG-3024) - Virtual poster presentation

                Daratumumab (Submitted by Janssen Biotech, Inc.):
                Cort

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                • K Offline
                  K Offline
                  KWC
                  wrote on sidst redigeret af
                  #874

                  Corticosteroid Tapering in Patients with Relapsed or Refractory Multiple Myeloma Receiving Subcutaneous Daratumumab: Part 3 of the Open-label, Multicenter, Phase 1b PAVO Study - Virtual poster presentation

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #875

                    Hvorfor nævner de ikke Teclistamab og Amivantamab? Det er ellers de tunge MM-drenge (og piger) der er med i Teclistamab.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #876

                      Nu virker søgemaskinen. Fandt denne her: A phase Ib study of TAK-079, an investigational anti-CD38 monoclonal antibody (mAb) in patients with relapsed/ refractory multiple myeloma (RRMM): Preliminary results. Skal satme under observation.

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #877

                        GSK's ADC er der også: DREAMM-2: Single-agent belantamab mafodotin (GSK2857916) in patients with relapsed/refractory multiple myeloma (RRMM) and high-risk (HR) cytogenetics.

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #878

                          Og i 1. linje: DREAMM-9: Phase III study of belantamab mafodotin plus VRd versus VRd alone in transplant-ineligible newly diagnosed multiple myeloma (TI NDMM).

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #879

                            Men dreamm-9 kan der umuligt være data fra. Det er nok bare en præsentation af studiet. Så sent som februar var dreamm-9 kun på planlægningsstadiet.

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #880

                              Mon ikke JNJ kunne vælge at holde lav profil mht kombinationsmulighederne til dara af konkurrencehensyn. De er i fuld gang med at afprøve https://clinicaltrials.gov/ct2/show/NCT04108195

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #881

                                Det kunne måske forklare Teclistamab, men ikke Amivantamab?

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #882

                                  BTD = late breaker

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #883

                                    ?

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                                    • G Offline
                                      G Offline
                                      GeorgeBest
                                      wrote on sidst redigeret af
                                      #884

                                      Bulder 21:33. Er det ikke ligegyldigt om Genmab fremhæver disse? De er jo med på ASCO.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #885

                                        De plejer at opregne revl og krat

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                                        • G Offline
                                          G Offline
                                          GeorgeBest
                                          wrote on sidst redigeret af
                                          #886

                                          Ja rigtigt

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