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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • K Offline
    K Offline
    KWC
    wrote on sidst redigeret af
    #870

    “Although this year’s ASCO will be a virtual conference due to the difficult and unprecedented circumstances, we are pleased that data on our proprietary pipeline and partnered programs has been accepted for presentation at this prestigious conference. We are particularly looking forward to the data presentation that will demonstrate continued solid progress in our development of epcoritamab (DuoBody-CD3xCD20),” said Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab.

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    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #871

      https://ir.genmab.com/news-releases/news-release-details/genmab-announces-data-be-presented-asco20-virtual-scientific

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      • K Offline
        K Offline
        KWC
        wrote on sidst redigeret af
        #872

        🙂

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        • K Offline
          K Offline
          KWC
          wrote on sidst redigeret af
          #873

          Epcoritamab:
          Epcoritamab (GEN3013; DuoBody-CD3×CD20) to induce complete response in patients with relapsed/ refractory B-NHL: Complete dose escalation data and efficacy results from a phase I/II trial - Virtual poster presentation

          Tisotumab Vedotin:
          Phase Ib/II trial of tisotumab vedotin ± bevacizumab, pembrolizumab, or carboplatin in recurrent or metastatic cervical cancer (innovaTV 205/ENGOT-cx8/GOG-3024) - Virtual poster presentation

          Daratumumab (Submitted by Janssen Biotech, Inc.):
          Cort

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          • K Offline
            K Offline
            KWC
            wrote on sidst redigeret af
            #874

            Corticosteroid Tapering in Patients with Relapsed or Refractory Multiple Myeloma Receiving Subcutaneous Daratumumab: Part 3 of the Open-label, Multicenter, Phase 1b PAVO Study - Virtual poster presentation

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #875

              Hvorfor nævner de ikke Teclistamab og Amivantamab? Det er ellers de tunge MM-drenge (og piger) der er med i Teclistamab.

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #876

                Nu virker søgemaskinen. Fandt denne her: A phase Ib study of TAK-079, an investigational anti-CD38 monoclonal antibody (mAb) in patients with relapsed/ refractory multiple myeloma (RRMM): Preliminary results. Skal satme under observation.

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #877

                  GSK's ADC er der også: DREAMM-2: Single-agent belantamab mafodotin (GSK2857916) in patients with relapsed/refractory multiple myeloma (RRMM) and high-risk (HR) cytogenetics.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #878

                    Og i 1. linje: DREAMM-9: Phase III study of belantamab mafodotin plus VRd versus VRd alone in transplant-ineligible newly diagnosed multiple myeloma (TI NDMM).

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #879

                      Men dreamm-9 kan der umuligt være data fra. Det er nok bare en præsentation af studiet. Så sent som februar var dreamm-9 kun på planlægningsstadiet.

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                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #880

                        Mon ikke JNJ kunne vælge at holde lav profil mht kombinationsmulighederne til dara af konkurrencehensyn. De er i fuld gang med at afprøve https://clinicaltrials.gov/ct2/show/NCT04108195

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #881

                          Det kunne måske forklare Teclistamab, men ikke Amivantamab?

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #882

                            BTD = late breaker

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #883

                              ?

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #884

                                Bulder 21:33. Er det ikke ligegyldigt om Genmab fremhæver disse? De er jo med på ASCO.

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #885

                                  De plejer at opregne revl og krat

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #886

                                    Ja rigtigt

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #887

                                      Men måske overlader de det til JnJ at reklamere

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #888

                                        Sidste år reklamerede JnJ for JnJ372. Så det gør de nok også i år.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #889

                                          Men det gjorde Genmab ikke, kan jeg se i arkiverne. Så det bliver nok, når JnJ udsender en meddelelse.

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