Genmab — Juni 2018

E_L

apparantly Halozyme expects

E_L

80%+ of the daratumumab dosing will convert to subcutaneous - spoke at the JMP Securities Life Science Conference

i did not listen to the call

bibob

@E L. 10.31. I think they are using Dara in the sunlotion. They all look very very healty to me. Especially the women.

bibob

@JKY

gentogen

Journal of Immunology. 1. maj, 2018: Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich rheumatoid arthritis, pre-rheumatoid arthritis and systemic lupus erythematosus. "Taken together, our data provides rationale for daratumumab in the treatment of RA and SLE"

Solsen

Det område har MEGA stort potentiale. Men vi mangler at se JNJ gøre noget.

Joakim_Von_And

Måske det får dem til at se fordelen ved at købe Genmab.

E_L

Nice article by Dr Plesner

E_L

Daratumumab for the Treatment of Multiple Myeloma - https://www.frontiersin.org/articles/10.3389/fimmu.2018.01228/full

E_L

"If further substantiated that an implication may be that daratumumab should be part of any anti-myeloma treatment. Given the pleiotropic effects of daratumumab, it is in fact difficult to imagine how a myeloma patient can become truly refractory to daratumumab."

Bulder

Mere fra Journal of Immunology. 1. maj, 2018: Dara i CLL, http://www.jimmunol.org/content/200/1_Supplement/58.17

E_L

just enough reading material until 14.00

E_L

so @Bulder , that is the Mayo clinic looking to do that trial with CLL then I gues

Raffles

Lad os håbe at JnJ snart får startet studier op med DARA i RA/SLE. Inden vi ser os om er det et år siden at JvdW nævnte at JnJ havde indsendt IND vedr DARA/RA!! Så det er på tide at komme videre:-)

Bulder

Yes, it looks like Mayo-people all over. Ohio State is currently running a combo with Ibrutinib https://www.clinicaltrials.gov/ct2/show/NCT03447808?term=daratumumab+cll&rank=1

Bulder

If only we could get something cooking in RA and other blood cancers than MM, that could compensate for poor solid outcome.

Investor13

Desværre fortsætter stigningen ikke i dag. TA mæssigt, er det vel vigtigt,
vi lukker over kurs 1000.

Bulder

Der ligger iøvrigt også et potentiale for ofa i RA. GSK nåede faktisk at gennemføre et fase 1 med sc ofa i RA. Og iflg Winkel er Novartis bevidst om dette.

Sukkeralf

Bulder selvfølgelig er Novartis bevidst om dette, når de har købt alle rettigheder - men tror det var sat igang, hvis man havde nogen interesse i det

Solsen

GSK er et fyord på på linie med fabrik