Genmab — Juni 2018

[bibob]

And Thanks to E L for another good finding.

[E_L]

how is Dara as sunlotion @bibob
?

[Parasitism]

Det skal siges, at jeg heller ikke havde regnet med så fint et luk, men det gjorde det kun endnu bedre. Jeg havde ikke regnet med at skulle være glad for et luk lige over 1000, men sådan er virkeligheden lige nu, og nu skal vi jo ikke se hullerne i osten

[Parasitism]

Og ja - god kamp til dem der kan se den og ikke skal arbejde

[JKY_VH]

God formiddag også til vores udsendte medarbejder i Malaga:-)

[E_L]

apparantly Halozyme expects

[E_L]

80%+ of the daratumumab dosing will convert to subcutaneous - spoke at the JMP Securities Life Science Conference

• i did not listen to the call

[bibob]

@E L. 10.31. I think they are using Dara in the sunlotion. They all look very very healty to me. Especially the women.

[bibob]

@JKY

[gentogen]

Journal of Immunology. 1. maj, 2018: Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich rheumatoid arthritis, pre-rheumatoid arthritis and systemic lupus erythematosus. "Taken together, our data provides rationale for daratumumab in the treatment of RA and SLE"

[Solsen]

Det område har MEGA stort potentiale. Men vi mangler at se JNJ gøre noget.

[Joakim_Von_And]

Måske det får dem til at se fordelen ved at købe Genmab.

[E_L]

Nice article by Dr Plesner

[E_L]

Daratumumab for the Treatment of Multiple Myeloma - https://www.frontiersin.org/articles/10.3389/fimmu.2018.01228/full

[E_L]

"If further substantiated that an implication may be that daratumumab should be part of any anti-myeloma treatment. Given the pleiotropic effects of daratumumab, it is in fact difficult to imagine how a myeloma patient can become truly refractory to daratumumab."

[Bulder]

Mere fra Journal of Immunology. 1. maj, 2018: Dara i CLL, http://www.jimmunol.org/content/200/1_Supplement/58.17

[E_L]

just enough reading material until 14.00

[E_L]

so @Bulder , that is the Mayo clinic looking to do that trial with CLL then I gues

[Raffles]

Lad os håbe at JnJ snart får startet studier op med DARA i RA/SLE. Inden vi ser os om er det et år siden at JvdW nævnte at JnJ havde indsendt IND vedr DARA/RA!! Så det er på tide at komme videre:-)

[Bulder]

Yes, it looks like Mayo-people all over. Ohio State is currently running a combo with Ibrutinib https://www.clinicaltrials.gov/ct2/show/NCT03447808?term=daratumumab+cll&rank=1