Genmab — Juni 2018

[Parasitism]

Og ja - god kamp til dem der kan se den og ikke skal arbejde

[JKY_VH]

God formiddag også til vores udsendte medarbejder i Malaga:-)

[E_L]

apparantly Halozyme expects

[E_L]

80%+ of the daratumumab dosing will convert to subcutaneous - spoke at the JMP Securities Life Science Conference

• i did not listen to the call

[bibob]

@E L. 10.31. I think they are using Dara in the sunlotion. They all look very very healty to me. Especially the women.

[bibob]

@JKY

[gentogen]

Journal of Immunology. 1. maj, 2018: Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich rheumatoid arthritis, pre-rheumatoid arthritis and systemic lupus erythematosus. "Taken together, our data provides rationale for daratumumab in the treatment of RA and SLE"

[Solsen]

Det område har MEGA stort potentiale. Men vi mangler at se JNJ gøre noget.

[Joakim_Von_And]

Måske det får dem til at se fordelen ved at købe Genmab.

[E_L]

Nice article by Dr Plesner

[E_L]

Daratumumab for the Treatment of Multiple Myeloma - https://www.frontiersin.org/articles/10.3389/fimmu.2018.01228/full

[E_L]

"If further substantiated that an implication may be that daratumumab should be part of any anti-myeloma treatment. Given the pleiotropic effects of daratumumab, it is in fact difficult to imagine how a myeloma patient can become truly refractory to daratumumab."

[Bulder]

Mere fra Journal of Immunology. 1. maj, 2018: Dara i CLL, http://www.jimmunol.org/content/200/1_Supplement/58.17

[E_L]

just enough reading material until 14.00

[E_L]

so @Bulder , that is the Mayo clinic looking to do that trial with CLL then I gues

[Raffles]

Lad os håbe at JnJ snart får startet studier op med DARA i RA/SLE. Inden vi ser os om er det et år siden at JvdW nævnte at JnJ havde indsendt IND vedr DARA/RA!! Så det er på tide at komme videre:-)

[Bulder]

Yes, it looks like Mayo-people all over. Ohio State is currently running a combo with Ibrutinib https://www.clinicaltrials.gov/ct2/show/NCT03447808?term=daratumumab+cll&rank=1

[Bulder]

If only we could get something cooking in RA and other blood cancers than MM, that could compensate for poor solid outcome.

[Investor13]

Desværre fortsætter stigningen ikke i dag. TA mæssigt, er det vel vigtigt,
vi lukker over kurs 1000.

[Bulder]

Der ligger iøvrigt også et potentiale for ofa i RA. GSK nåede faktisk at gennemføre et fase 1 med sc ofa i RA. Og iflg Winkel er Novartis bevidst om dette.