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Genmab — Juni 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • J Offline
    J Offline
    Joakim_Von_And
    wrote on sidst redigeret af
    #1860

    Måske det får dem til at se fordelen ved at købe Genmab.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1861

      Nice article by Dr Plesner

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1862

        Daratumumab for the Treatment of Multiple Myeloma - https://www.frontiersin.org/articles/10.3389/fimmu.2018.01228/full

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1863

          "If further substantiated that an implication may be that daratumumab should be part of any anti-myeloma treatment. Given the pleiotropic effects of daratumumab, it is in fact difficult to imagine how a myeloma patient can become truly refractory to daratumumab."

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #1864

            Mere fra Journal of Immunology. 1. maj, 2018: Dara i CLL, http://www.jimmunol.org/content/200/1_Supplement/58.17

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #1865

              just enough reading material until 14.00 😉

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1866

                so @Bulder , that is the Mayo clinic looking to do that trial with CLL then I gues

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                • R Offline
                  R Offline
                  Raffles
                  wrote on sidst redigeret af
                  #1867

                  Lad os håbe at JnJ snart får startet studier op med DARA i RA/SLE. Inden vi ser os om er det et år siden at JvdW nævnte at JnJ havde indsendt IND vedr DARA/RA!! Så det er på tide at komme videre:-)

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #1868

                    Yes, it looks like Mayo-people all over. Ohio State is currently running a combo with Ibrutinib https://www.clinicaltrials.gov/ct2/show/NCT03447808?term=daratumumab+cll&rank=1

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #1869

                      If only we could get something cooking in RA and other blood cancers than MM, that could compensate for poor solid outcome.

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                      • I Offline
                        I Offline
                        Investor13
                        wrote on sidst redigeret af
                        #1870

                        Desværre fortsætter stigningen ikke i dag. TA mæssigt, er det vel vigtigt,
                        vi lukker over kurs 1000.

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #1871

                          Der ligger iøvrigt også et potentiale for ofa i RA. GSK nåede faktisk at gennemføre et fase 1 med sc ofa i RA. Og iflg Winkel er Novartis bevidst om dette.

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #1872

                            Bulder selvfølgelig er Novartis bevidst om dette, når de har købt alle rettigheder - men tror det var sat igang, hvis man havde nogen interesse i det

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #1873

                              GSK er et fyord på på linie med fabrik

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #1874

                                og dragen LD

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                                • M Offline
                                  M Offline
                                  mobbyduck1
                                  wrote on sidst redigeret af
                                  #1875

                                  hehe

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1876

                                    Godt klar over at GSK er ugleset her på sitet. Men det var trods alt dem, der udviklede sc ofa. Der ligger 3 IV ofa i RA på CT, som blev afbrudt, fordi man ville gå over til sc. Og 1 gennemført sc i RA. Som herefter Novartis indtil videre har ignoreret.

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                                    • J Offline
                                      J Offline
                                      JKY_VH
                                      wrote on sidst redigeret af
                                      #1877

                                      Det var vel også der tilførte os 800 mio eller noget i den retning, da vi var ved at gå på r.... ?

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                                      • J Offline
                                        J Offline
                                        JKY_VH
                                        wrote on sidst redigeret af
                                        #1878

                                        dem

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                                        • royalR Offline
                                          royalR Offline
                                          royal
                                          wrote on sidst redigeret af
                                          #1879

                                          Hunden, ikke at forglemme. 🙂

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