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Genmab — April 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #1252

    Jeg er lidt forvirret. I januar skriver Novod: We expect the first combo studies of JNJ-283 and Darzalex to be initiated in 2018. Og nu har vi pludseligt et fase 2/3 studie, som faktisk er færdigt!

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    • SolsenS Offline
      SolsenS Offline
      Solsen
      wrote on sidst redigeret af
      #1253

      Tror du ikke det er solide han omtaler.

      1 Reply Last reply
      0
      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #1254

        Selvfølgelig. Tak Solsen 🙂

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        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #1255

          Holdt foredrag i Svinningehallen her til aften. Genmab er stadig en folkeaktie. 🙂

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          • M Offline
            M Offline
            Mayflower
            wrote on sidst redigeret af
            #1256

            Godmorgen 🙂

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #1257

              Access denied | www.fiercebiotech.com used Cloudflare to restrict access | www.fiercebiotech.com | Cloudflare

              favicon

              (www.fiercebiotech.com)

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #1258

                Måske også et lille slag i ansigtet til ADCT-301. For dem der følger Bergenbio så rart at det nye AXL ADCT-601 bruger den nye linker teknologi

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                0
                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #1259

                  Lidt fra Firstword: Final thoughts

                  Of course, one of the most high-profile reckonings for an ADC- and the PBD dimers used by ADC Therapeutics- will come from Stemcentrx and AbbVie's highly anticipated TRITON study of Rova-T. Unfortunately, AbbVie has already signalled that the outcome with be poor for the small-cell lung cancer candidate (SCLC);

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #1260

                    last month it disclosed some mixed data and indicated it would not be pursuing accelerated approval for the compound. That said, companies like ADC Therapeutics can be confident that as long as the readout isn't dripping with safety concerns, their platform should still have legs

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                    0
                    • Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktør
                      wrote on sidst redigeret af
                      #1261

                      God morgen. 🙂

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                      0
                      • P Offline
                        P Offline
                        polle1
                        wrote on sidst redigeret af
                        #1262

                        God morgen 🙂

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                        0
                        • B Offline
                          B Offline
                          bibob
                          wrote on sidst redigeret af
                          #1263

                          God morgen :-).

                          1 Reply Last reply
                          0
                          • P Offline
                            P Offline
                            Parasitism
                            wrote on sidst redigeret af
                            #1264

                            God morgen 🙂

                            1 Reply Last reply
                            0
                            • R Offline
                              R Offline
                              rex_pacis
                              wrote on sidst redigeret af
                              #1265

                              God morgen 🙂

                              1 Reply Last reply
                              0
                              • J Offline
                                J Offline
                                JohnW
                                wrote on sidst redigeret af
                                #1266

                                God morgen 🙂 Noget nyt om SH-tallene, eller er det blevet en non-event?

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                                0
                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #1267

                                  Sukker, er det PDB'en eller er det linkeren, der er problemet?

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1268

                                    PBD

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                                    0
                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #1269

                                      Det er nok mere komplekst end som så - tænker mest linkeren, men man skal nok grave lidt dybere i det. Som jeg husker det er PBD warheads ca. 1000 gange mere potent end eksempelvis MMAE, så det kræver jo at giften i endnu højere grad leveres det rette sted

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1270

                                        Av, det var voldsomt. Nu var lungeødem et af problemerne. Hvordan ser det ud med cd25 i lungerne - ved du det?

                                        1 Reply Last reply
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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #1271

                                          Jeg kan se, Genmab skriver: limited expression on normal tissues

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                                          0

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