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Genmab — April 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #1251

    Jeg spørger Winkel på Q&A.

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    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #1252

      Jeg er lidt forvirret. I januar skriver Novod: We expect the first combo studies of JNJ-283 and Darzalex to be initiated in 2018. Og nu har vi pludseligt et fase 2/3 studie, som faktisk er færdigt!

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      0
      • SolsenS Offline
        SolsenS Offline
        Solsen
        wrote on sidst redigeret af
        #1253

        Tror du ikke det er solide han omtaler.

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        0
        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #1254

          Selvfølgelig. Tak Solsen 🙂

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          0
          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #1255

            Holdt foredrag i Svinningehallen her til aften. Genmab er stadig en folkeaktie. 🙂

            1 Reply Last reply
            0
            • M Offline
              M Offline
              Mayflower
              wrote on sidst redigeret af
              #1256

              Godmorgen 🙂

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              0
              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #1257

                Access denied | www.fiercebiotech.com used Cloudflare to restrict access | www.fiercebiotech.com | Cloudflare

                favicon

                (www.fiercebiotech.com)

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #1258

                  Måske også et lille slag i ansigtet til ADCT-301. For dem der følger Bergenbio så rart at det nye AXL ADCT-601 bruger den nye linker teknologi

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                  0
                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #1259

                    Lidt fra Firstword: Final thoughts

                    Of course, one of the most high-profile reckonings for an ADC- and the PBD dimers used by ADC Therapeutics- will come from Stemcentrx and AbbVie's highly anticipated TRITON study of Rova-T. Unfortunately, AbbVie has already signalled that the outcome with be poor for the small-cell lung cancer candidate (SCLC);

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                    0
                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #1260

                      last month it disclosed some mixed data and indicated it would not be pursuing accelerated approval for the compound. That said, companies like ADC Therapeutics can be confident that as long as the readout isn't dripping with safety concerns, their platform should still have legs

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                      0
                      • Helge_LarsenPI-redaktørH Offline
                        Helge_LarsenPI-redaktørH Offline
                        Helge_LarsenPI-redaktør
                        wrote on sidst redigeret af
                        #1261

                        God morgen. 🙂

                        1 Reply Last reply
                        0
                        • P Offline
                          P Offline
                          polle1
                          wrote on sidst redigeret af
                          #1262

                          God morgen 🙂

                          1 Reply Last reply
                          0
                          • B Offline
                            B Offline
                            bibob
                            wrote on sidst redigeret af
                            #1263

                            God morgen :-).

                            1 Reply Last reply
                            0
                            • P Offline
                              P Offline
                              Parasitism
                              wrote on sidst redigeret af
                              #1264

                              God morgen 🙂

                              1 Reply Last reply
                              0
                              • R Offline
                                R Offline
                                rex_pacis
                                wrote on sidst redigeret af
                                #1265

                                God morgen 🙂

                                1 Reply Last reply
                                0
                                • J Offline
                                  J Offline
                                  JohnW
                                  wrote on sidst redigeret af
                                  #1266

                                  God morgen 🙂 Noget nyt om SH-tallene, eller er det blevet en non-event?

                                  1 Reply Last reply
                                  0
                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1267

                                    Sukker, er det PDB'en eller er det linkeren, der er problemet?

                                    1 Reply Last reply
                                    0
                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1268

                                      PBD

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                                      0
                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #1269

                                        Det er nok mere komplekst end som så - tænker mest linkeren, men man skal nok grave lidt dybere i det. Som jeg husker det er PBD warheads ca. 1000 gange mere potent end eksempelvis MMAE, så det kræver jo at giften i endnu højere grad leveres det rette sted

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                                        0
                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #1270

                                          Av, det var voldsomt. Nu var lungeødem et af problemerne. Hvordan ser det ud med cd25 i lungerne - ved du det?

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                                          0

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