Genmab — April 2018
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Det har Winkel talt om ved flere lejligheder. Da der er et udækket behov for et medikament i metastatisk LMHK, vil muligheden være til stede, hvis data er gode nok. Men studiet er end ikke begyndt at rekruttere https://www.clinicaltrials.gov/ct2/show/NCT03438396?term=tisotumab+vedotin&rank=3 Så tidligst 2021 er hvad jeg har hørt.
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https://clinicaltrials.gov/ct2/show/NCT03357952?term=JNJ-63723283&rank=2 Pd1 plus dara har primary completion date 15. Marts i år....
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Pudsigt, i pressemeddelelsen skriver Genmab at det er et fase 2/3 studie. På ct står det som fase 1?? https://clinicaltrials.gov/ct2/show/NCT03357952?term=mmy2036&rank=1 Men det er måske det, de mener med et multi-fase-studie. Og at effekt-delen i part 3 er nok til at file på? Der er jo pænt mange pts med.
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Holdt foredrag i Svinningehallen her til aften. Genmab er stadig en folkeaktie.
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Lidt fra Firstword: Final thoughts
Of course, one of the most high-profile reckonings for an ADC- and the PBD dimers used by ADC Therapeutics- will come from Stemcentrx and AbbVie's highly anticipated TRITON study of Rova-T. Unfortunately, AbbVie has already signalled that the outcome with be poor for the small-cell lung cancer candidate (SCLC);
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last month it disclosed some mixed data and indicated it would not be pursuing accelerated approval for the compound. That said, companies like ADC Therapeutics can be confident that as long as the readout isn't dripping with safety concerns, their platform should still have legs
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God morgen.
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