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Genmab — April 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • SolsenS Offline
    SolsenS Offline
    Solsen
    wrote on sidst redigeret af
    #1253

    Tror du ikke det er solide han omtaler.

    1 Reply Last reply
    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #1254

      Selvfølgelig. Tak Solsen 🙂

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      0
      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #1255

        Holdt foredrag i Svinningehallen her til aften. Genmab er stadig en folkeaktie. 🙂

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        • M Offline
          M Offline
          Mayflower
          wrote on sidst redigeret af
          #1256

          Godmorgen 🙂

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          0
          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #1257

            Access denied | www.fiercebiotech.com used Cloudflare to restrict access | www.fiercebiotech.com | Cloudflare

            favicon

            (www.fiercebiotech.com)

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #1258

              Måske også et lille slag i ansigtet til ADCT-301. For dem der følger Bergenbio så rart at det nye AXL ADCT-601 bruger den nye linker teknologi

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              0
              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #1259

                Lidt fra Firstword: Final thoughts

                Of course, one of the most high-profile reckonings for an ADC- and the PBD dimers used by ADC Therapeutics- will come from Stemcentrx and AbbVie's highly anticipated TRITON study of Rova-T. Unfortunately, AbbVie has already signalled that the outcome with be poor for the small-cell lung cancer candidate (SCLC);

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                0
                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #1260

                  last month it disclosed some mixed data and indicated it would not be pursuing accelerated approval for the compound. That said, companies like ADC Therapeutics can be confident that as long as the readout isn't dripping with safety concerns, their platform should still have legs

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                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #1261

                    God morgen. 🙂

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                    0
                    • P Offline
                      P Offline
                      polle1
                      wrote on sidst redigeret af
                      #1262

                      God morgen 🙂

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                      0
                      • B Offline
                        B Offline
                        bibob
                        wrote on sidst redigeret af
                        #1263

                        God morgen :-).

                        1 Reply Last reply
                        0
                        • P Offline
                          P Offline
                          Parasitism
                          wrote on sidst redigeret af
                          #1264

                          God morgen 🙂

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                          0
                          • R Offline
                            R Offline
                            rex_pacis
                            wrote on sidst redigeret af
                            #1265

                            God morgen 🙂

                            1 Reply Last reply
                            0
                            • J Offline
                              J Offline
                              JohnW
                              wrote on sidst redigeret af
                              #1266

                              God morgen 🙂 Noget nyt om SH-tallene, eller er det blevet en non-event?

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                              0
                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #1267

                                Sukker, er det PDB'en eller er det linkeren, der er problemet?

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                                0
                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #1268

                                  PBD

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                                  0
                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #1269

                                    Det er nok mere komplekst end som så - tænker mest linkeren, men man skal nok grave lidt dybere i det. Som jeg husker det er PBD warheads ca. 1000 gange mere potent end eksempelvis MMAE, så det kræver jo at giften i endnu højere grad leveres det rette sted

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                                    0
                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1270

                                      Av, det var voldsomt. Nu var lungeødem et af problemerne. Hvordan ser det ud med cd25 i lungerne - ved du det?

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                                      0
                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1271

                                        Jeg kan se, Genmab skriver: limited expression on normal tissues

                                        1 Reply Last reply
                                        0
                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #1272

                                          Det er vel noget i stil med dette Jan mener er problemet med CD38-ADC, at CD38 er udtrykt i lungerne

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                                          0

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