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Genmab — September 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #337

    Omvendt har dara+imid nærmest synergieffekt. Det sås ved dara+pom.

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    0
    • SolsenS Offline
      SolsenS Offline
      Solsen
      wrote on sidst redigeret af
      #338

      Mon ikke det er CRS, der er problemet. Vi har dog set at man i CAR-T behandlingen kan mindske de problemer med anti Il-6 behandling. CRS=cytokine release syndrom.

      1 Reply Last reply
      0
      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #339

        Whatever the problem is, if dara works well enough without PD1 t
        he package will be much cheaper...

        1 Reply Last reply
        0
        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #340

          Der er en kilometerlang liste over Keytruda's genvordigheder, men en søgning på CRS og cytokine gav ikke hug. http://investors.merck.com/news/press-release-details/2017/Merck-Provides-Further-Update-on-Three-Multiple-Myeloma-Studies-Evaluating-KEYTRUDA-pembrolizumab-in-Combination-with-Pomalidomide-or-Lenalidomide/default.aspx

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          0
          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #341

            https://dev.hematology.org/Thehematologist/Diffusion/7617.aspx Fra et fase 2 Pomalidomider/PD1 forsøg. 40% grade 3-4 SAE.

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #342

              vi må afvente den nærmere afklaring

              1 Reply Last reply
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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #343

                Merck buys Rigontec ; another immuno-oncology combo?
                http://www.epvantage.com/Universal/View.aspx?type=Story&id=729882&isEPVantage=yes

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #344

                  meanwhile, the company that had to put Opdivo on partial clinical hold , has some succes with.... Opdivo 😉 https://investors.bms.com/iframes/press-releases/press-release-details/2017/CheckMate--214-Study-Evaluating-Opdivo-in-Combination-with-Yervoy-Stopped-Early-for-Demonstrating-Overall-Survival-Benefit-in-Patients-with-Previously-Untreated-Advanced-or-Metastatic-Renal-Cell-Carcinoma/default.aspx

                  1 Reply Last reply
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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #345

                    BMY +5% http://www.nasdaq.com/article/bristolmyers-squibb-bmy-has-risen-to-a-new-high-on-phase-3-study-news-20170907-00940

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                    0
                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #346

                      Thanks E L - thats why Exelixis falls 10%

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                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #347

                        Access denied | www.fiercebiotech.com used Cloudflare to restrict access | www.fiercebiotech.com | Cloudflare

                        favicon

                        (www.fiercebiotech.com)

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                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #348

                          At specifik ramme de immunsuppressive T-regs virker mere smart 😉

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                          0
                          • T Offline
                            T Offline
                            tianc
                            wrote on sidst redigeret af
                            #349

                            Sukkeralf -Kan jeg lokke dig til at forklare kort, hvorfor Exel falder på dette?

                            1 Reply Last reply
                            0
                            • Legolas23L Offline
                              Legolas23L Offline
                              Legolas23
                              wrote on sidst redigeret af
                              #350

                              God morn

                              1 Reply Last reply
                              0
                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #351

                                God morgen. 🙂

                                1 Reply Last reply
                                0
                                • Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktør
                                  wrote on sidst redigeret af
                                  #352

                                  God morgen. 🙂

                                  1 Reply Last reply
                                  0
                                  • M Offline
                                    M Offline
                                    Mogan
                                    wrote on sidst redigeret af
                                    #353

                                    God morgen 🙂

                                    1 Reply Last reply
                                    0
                                    • J Offline
                                      J Offline
                                      Jedi
                                      wrote on sidst redigeret af
                                      #354

                                      Her er en opsummering af sammenhæng mellem Exel og Opdivo/Yervoy succes i RCC https://seekingalpha.com/news/3294186-exelixis-9-percent-bristol-myers-successful-study-opdivo-yervoy-rcc?app=1&uprof=45&dr=1#email_link

                                      1 Reply Last reply
                                      0
                                      • J Offline
                                        J Offline
                                        Jedi
                                        wrote on sidst redigeret af
                                        #355

                                        Sorry - havde ikke set at Sukkeralf allerede har svaret udførligt i Biotek chatten

                                        1 Reply Last reply
                                        0
                                        • C Offline
                                          C Offline
                                          CPH
                                          wrote on sidst redigeret af
                                          #356

                                          Fin stigning i dag, - med ab på købersiden. Der er ved at være golden cross hvor 20 dages glidende gennemsnit går op igennem 50 dages glidende gennemsnit. Til dem der følger med i det.. 🙂

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