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Genmab — September 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #336

    Er der nogen, der ved hvad Keytruda-patienten egentlig døde af?

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    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #337

      Omvendt har dara+imid nærmest synergieffekt. Det sås ved dara+pom.

      1 Reply Last reply
      0
      • SolsenS Offline
        SolsenS Offline
        Solsen
        wrote on sidst redigeret af
        #338

        Mon ikke det er CRS, der er problemet. Vi har dog set at man i CAR-T behandlingen kan mindske de problemer med anti Il-6 behandling. CRS=cytokine release syndrom.

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        0
        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #339

          Whatever the problem is, if dara works well enough without PD1 t
          he package will be much cheaper...

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          0
          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #340

            Der er en kilometerlang liste over Keytruda's genvordigheder, men en søgning på CRS og cytokine gav ikke hug. http://investors.merck.com/news/press-release-details/2017/Merck-Provides-Further-Update-on-Three-Multiple-Myeloma-Studies-Evaluating-KEYTRUDA-pembrolizumab-in-Combination-with-Pomalidomide-or-Lenalidomide/default.aspx

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            0
            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #341

              https://dev.hematology.org/Thehematologist/Diffusion/7617.aspx Fra et fase 2 Pomalidomider/PD1 forsøg. 40% grade 3-4 SAE.

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #342

                vi må afvente den nærmere afklaring

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                0
                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #343

                  Merck buys Rigontec ; another immuno-oncology combo?
                  http://www.epvantage.com/Universal/View.aspx?type=Story&id=729882&isEPVantage=yes

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #344

                    meanwhile, the company that had to put Opdivo on partial clinical hold , has some succes with.... Opdivo 😉 https://investors.bms.com/iframes/press-releases/press-release-details/2017/CheckMate--214-Study-Evaluating-Opdivo-in-Combination-with-Yervoy-Stopped-Early-for-Demonstrating-Overall-Survival-Benefit-in-Patients-with-Previously-Untreated-Advanced-or-Metastatic-Renal-Cell-Carcinoma/default.aspx

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                    0
                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #345

                      BMY +5% http://www.nasdaq.com/article/bristolmyers-squibb-bmy-has-risen-to-a-new-high-on-phase-3-study-news-20170907-00940

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                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #346

                        Thanks E L - thats why Exelixis falls 10%

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                        0
                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #347

                          Access denied | www.fiercebiotech.com used Cloudflare to restrict access | www.fiercebiotech.com | Cloudflare

                          favicon

                          (www.fiercebiotech.com)

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                          0
                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #348

                            At specifik ramme de immunsuppressive T-regs virker mere smart 😉

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                            0
                            • T Offline
                              T Offline
                              tianc
                              wrote on sidst redigeret af
                              #349

                              Sukkeralf -Kan jeg lokke dig til at forklare kort, hvorfor Exel falder på dette?

                              1 Reply Last reply
                              0
                              • Legolas23L Offline
                                Legolas23L Offline
                                Legolas23
                                wrote on sidst redigeret af
                                #350

                                God morn

                                1 Reply Last reply
                                0
                                • B Offline
                                  B Offline
                                  bibob
                                  wrote on sidst redigeret af
                                  #351

                                  God morgen. 🙂

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                                  0
                                  • Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktør
                                    wrote on sidst redigeret af
                                    #352

                                    God morgen. 🙂

                                    1 Reply Last reply
                                    0
                                    • M Offline
                                      M Offline
                                      Mogan
                                      wrote on sidst redigeret af
                                      #353

                                      God morgen 🙂

                                      1 Reply Last reply
                                      0
                                      • J Offline
                                        J Offline
                                        Jedi
                                        wrote on sidst redigeret af
                                        #354

                                        Her er en opsummering af sammenhæng mellem Exel og Opdivo/Yervoy succes i RCC https://seekingalpha.com/news/3294186-exelixis-9-percent-bristol-myers-successful-study-opdivo-yervoy-rcc?app=1&uprof=45&dr=1#email_link

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                                        0
                                        • J Offline
                                          J Offline
                                          Jedi
                                          wrote on sidst redigeret af
                                          #355

                                          Sorry - havde ikke set at Sukkeralf allerede har svaret udførligt i Biotek chatten

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                                          0

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