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Genmab — Juli 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • nohopeN Offline
    nohopeN Offline
    nohope
    wrote on sidst redigeret af
    #740

    Farligt at have flere chatsider åbne samtidigt.....:-)

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    • DarvinD Offline
      DarvinD Offline
      Darvin
      wrote on sidst redigeret af
      #741

      Lige tilbage igen: i CITI's mål på de 1.800 er MM (og øvrig pipeline (Tisotumab mv) discounted (derisced) med 15 pct) og først derudover 259 for foreløbig mulighed i solide tumorer. Altså1800 plus 259. De regner jo så med en derisked DCF kurs på pt 3.500 :-). Og misforstå mig ikke - jeg er ikke ved at indregne "alt" - men perspektiv er der til fulde

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      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #742

        God morgen. 🙂

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #743

          God morgen. 🙂

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          • P Offline
            P Offline
            polle1
            wrote on sidst redigeret af
            #744

            God morgen 🙂

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            • M Offline
              M Offline
              Mogan
              wrote on sidst redigeret af
              #745

              God morgen:-) Lidt læsning inden markedet åbner. https://www.nytimes.com/2017/07/23/health/gene-therapy-cancer.html?mwrsm=Email

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #746

                Vi kan nok godt være enige om at det ikke revolutionere glioblastoma behandlingen, desværre.

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                • M Offline
                  M Offline
                  Mogan
                  wrote on sidst redigeret af
                  #747

                  Solsen: Enig, lang vej endnu.

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #748

                    Også enig Solsen. Glioblastoma er jo næsten det samme som en virus i selve kontrolcenteret i en computer. Meget svært at kontrollere og " rense ". Drugs skal virkelig være designet til opgaven. Måske med nanopartikler. ?

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                    • B Offline
                      B Offline
                      BiotechPro
                      wrote on sidst redigeret af
                      #749

                      Carnegie genoptager dækning af GEN med Hold, target 1392

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                      • B Offline
                        B Offline
                        BiotechPro
                        wrote on sidst redigeret af
                        #750

                        CAR: The current success of Darzalex for multiple myeloma has transformed the company. We expect revenue to reach DKK14.7bn in 2026, a compound annual growth rate of 20% from a base of DKK2.3bn in 2016. We estimate that 84% of revenue in 2026 will be based on Darzalex royalties. In multiple myeloma alone, we forecast unadjusted peak sales of USD8.6bn against consensus of about USD8bn.

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                        • B Offline
                          B Offline
                          BiotechPro
                          wrote on sidst redigeret af
                          #751

                          CAR: The next transformation of the Genmab story could be the development of Arzerra for multiple sclerosis and new antibody-based cancer treatments.

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                          • B Offline
                            B Offline
                            BiotechPro
                            wrote on sidst redigeret af
                            #752

                            CAR: Genmab currently has two projects in early clinical development (tisotumab vedotin and HuMax-AXL-ADX) and has said that two more projects from its pre-clinical pipeline will advance to the clinic in H2(17).

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                            • B Offline
                              B Offline
                              BiotechPro
                              wrote on sidst redigeret af
                              #753

                              CAR: Based on our estimates the current share price fully discounts our base case SOTP valuation. Our bull case shows potential upside to DKK2,572 per share, primarily driven by new indications beyond multiple myeloma, particularly solid tumours. However, we find the risk/reward asymmetrical. Our bear case points to DKK858 per share.

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                              • B Offline
                                B Offline
                                BiotechPro
                                wrote on sidst redigeret af
                                #754

                                CAR: The next important data point is likely to be announced in Q3(17) when the interim analysis of the ALCYONE trial (Da-VMP versus VMP in patients ineligible for autologous stem cell therapy) is expected.

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                                • B Offline
                                  B Offline
                                  BiotechPro
                                  wrote on sidst redigeret af
                                  #755

                                  CAR: The ALCYONE trial I is the first of three phase III trials of Darzalex in first line multiple myeloma to report data. Our current probability of success for Darzalex in first line multiple myeloma is 85%. If we increase it to 100%, Darzalex NPV increases by DKK102 per share.

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                                  • F Offline
                                    F Offline
                                    flottenschmecker
                                    wrote on sidst redigeret af
                                    #756

                                    Tak for det BiotechPro. Ud fra dine kommentarer ligner det mest en "ikke-analyse" fra Carnegies side. Vi tror ikke en skid på Gen ud over dara...

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                                    • F Offline
                                      F Offline
                                      flottenschmecker
                                      wrote on sidst redigeret af
                                      #757

                                      Deres seneste analyse var ikke synderligt tynget af indsigt eller viden. Den her analyse ser også ud til at man bruger "obligationsmodellen" til at estimere pengestrømmen...

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                                      • Legolas23L Offline
                                        Legolas23L Offline
                                        Legolas23
                                        wrote on sidst redigeret af
                                        #758

                                        En endelig godkendelse for ALCYONE vil udløse 102 kr og være lig med de sidste 15% i analysen. Når man ved patientgrunflaget bliver fordoblet i 1. Linie er det også lavt og ikke realistisk sat.

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                                        • F Offline
                                          F Offline
                                          flottenschmecker
                                          wrote on sidst redigeret af
                                          #759

                                          Det er lige det. Seler og livrem analyser i biotek er i bedste fald ubrugelige

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