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Genmab — Maj 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • K Offline
    K Offline
    kkjoel
    wrote on sidst redigeret af
    #1038

    Just a moment...

    favicon

    (www.investor.jnj.com)

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    • T Offline
      T Offline
      transalp
      wrote on sidst redigeret af
      #1039

      Go morgen.. 🙂 mit kaffegrums siger at vi holder os i det grønne idag.. der er for meget damp på maskinen, købere til de evt ekstra aktier der kommer i dag.. 🙂

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      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #1040

        God morgen. 🙂

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #1041

          God morgen. 🙂

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #1042

            dara vs Sarclisa (GEN): https://www.proinvestor.com/debat/84218#84220

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            • B Offline
              B Offline
              bibob
              wrote on sidst redigeret af
              #1043

              Nyt studie med Ofatumumab. ( ARTIOS ) . Ved ikke om det har været postet. https://www.clinicaltrials.gov/ct2/show/NCT04353492?term=Ofatumumab&draw=1&rank=4

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1044

                From BioNTech SE (BNTX) Q1 2020 Earnings Call Transcript https://www.fool.com/earnings/call-transcripts/2020/05/13/biontech-se-bntx-q1-2020-earnings-call-transcript.aspx

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1045

                  "For our next-generation checkpoint-immune modulatory program partnered with Genmab, the ongoing trial with BNT311, the PD-L1x4-1BB dual body, continues to advance rapidly, as the expansion cohort has been initiated. Data from this Phase 1/2 trial in multiple solid tumors is expected in the second half of this year. We expect the updates to include dose escalation and safety data from the trial. We are excited about this program.

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1046

                    We believe it has broad potential in a range of solid tumors, including those where checkpoint therapy is currently established but also more difficult tumors where first-generation checkpoint inhibitors have not been as successful. This bispecific antibody has outperformed conventional checkpoint inhibitors in preclinical animal models. We have seen strong evidence in the preclinical setting of its ability to amplify the effect of our vaccines as well."

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1047

                      vaccines...?

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1048

                        BioNTech is trying PD1-/PD-L1
                        Inhibitors with their mRNA Cancer vaccines in Melanoma; i wonder if this could be an area where the PD-L1x4-1BB duobody could be used instead?

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1049

                          I Guess so E L based on your comments from the transcript - lots of opportunities going forward with this program if the initial phase I/II data are good

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #1050

                            And both Genmab and BioNTech seems quite thrilled so far - actualy it could be even a bigger product than Darzalex but thats years ahead from now and lots of hills or even mountains to climb

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                            • nohopeN Offline
                              nohopeN Offline
                              nohope
                              wrote on sidst redigeret af
                              #1051

                              Has anybody ever gotten an approval for a mRNA vaccine ?

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #1052

                                no, not yet

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                                • nohopeN Offline
                                  nohopeN Offline
                                  nohope
                                  wrote on sidst redigeret af
                                  #1053

                                  Well, I guess this what they call a really long shot in english.

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #1054

                                    sure. on the other hand, there has never been as much focus and as much research into mRNA as now, due to Covid, surely could lead to something

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                                    • nohopeN Offline
                                      nohopeN Offline
                                      nohope
                                      wrote on sidst redigeret af
                                      #1055

                                      Yes, really comforting right ? The destiny of the world depends on a technique that has never had a positive outcome.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #1056

                                        i am not so sure about that lol, many other trials going on. But , as they say, under pressure everything becomes fluid, let's 'hope' they are successful 😉

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #1057

                                          the main focus for now for GEN1046
                                          will be solid tumors anyway
                                          .

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