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Genmab — September 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #1524

    Man kan vel heller ikke forvente at en dara-skeptiker nu skal kaste sig næsegrus i støvet 😉

    1 Reply Last reply
    0
    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #1525

      Nina Shah kommenterer på isa-pom-dex https://twitter.com/ninashah33/status/1172883924038479874?s=21

      1 Reply Last reply
      0
      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #1526

        Omar Nadeem MD. " Dara sq needs to be approved ASAP. 🙂

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #1527

          Fandt lige det her: FDA informs the applicant of a Priority Review designation within 60 days of the receipt of the original BLA. - Og det var i tirsdags. Har skrevet og spurgt Andrew Carlsen om de overhovedet har søgt. https://www.fda.gov/patients/fast-track-breakthrough-therapy-accelerated-approval-priority-review/priority-review

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #1528

            ... om sc dara altså

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            0
            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #1529

              New DARZALEX® (daratumumab) Data from GRIFFIN Study Show High Response Rate and Depth of Response in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant-Eligible https://www.prnewswire.com/news-releases/new-darzalex-daratumumab-data-from-griffin-study-show-high-response-rate-and-depth-of-response-in-patients-with-newly-diagnosed-multiple-myeloma-who-are-transplant-eligible-300918272.html

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              0
              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1530

                looks like very good data.to me

                1 Reply Last reply
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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1531

                  it also mentions PLEIADES data has been included in the submission of the SC BLA to the FDA

                  1 Reply Last reply
                  0
                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1532

                    https://twitter.com/notthatjensmith/status/1172894272238104578

                    1 Reply Last reply
                    0
                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1533

                      https://twitter.com/theMMRF/status/1173218606643142656

                      1 Reply Last reply
                      0
                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1534

                        https://twitter.com/MM_Hub/status/1172866987040677888

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                        0
                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #1535

                          Most impressing is the doubling of MRDneg in Griffin.

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                          0
                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #1536

                            ... more than doubling it is

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                            • P Offline
                              P Offline
                              peter12
                              wrote on sidst redigeret af
                              #1537

                              Lidt bedre end fra Ph1 https://www.targetedonc.com/investigator-perspectives/frontline-mm/the-griffin-trial-in-multiple-myeloma

                              1 Reply Last reply
                              0
                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #1538

                                Dara kan stort set ikke undgå at blive en del af frontline i alle kombi som de parres med. Alt bliver bedre. " vil De have det bedste udkomme. - bare tilsæt Dara. " 😄

                                1 Reply Last reply
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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #1539

                                  Det har været nogle gode dage at være Genmab aktionær. Kursen skal nok afspejle fremgangene på et tidspunkt.

                                  1 Reply Last reply
                                  0
                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1540

                                    Nu er spørgsmålet så om Griffin kommer på compendia listing og dermed kan bruges off label. Der går en rum tid før der ligger Perseus data, der kan files på.

                                    1 Reply Last reply
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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #1541

                                      Er det ikke mærkeligt at fastsætte et endpoint og statistisk metode til at vurdere forsøget på, hvis ikke der er en ide med det.

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                                      0
                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1542

                                        De 41% der fik IRR i Griffin, får vi næste gang beydeligt lavere, da både Perseus og Cepheus kører med sc dara.

                                        1 Reply Last reply
                                        0
                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #1543

                                          Hvad mener du solsen?

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                                          0

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