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Genmab — September 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #1523

    Ja, men de bliver trods alt nævnt

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #1524

      Man kan vel heller ikke forvente at en dara-skeptiker nu skal kaste sig næsegrus i støvet 😉

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      0
      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #1525

        Nina Shah kommenterer på isa-pom-dex https://twitter.com/ninashah33/status/1172883924038479874?s=21

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #1526

          Omar Nadeem MD. " Dara sq needs to be approved ASAP. 🙂

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #1527

            Fandt lige det her: FDA informs the applicant of a Priority Review designation within 60 days of the receipt of the original BLA. - Og det var i tirsdags. Har skrevet og spurgt Andrew Carlsen om de overhovedet har søgt. https://www.fda.gov/patients/fast-track-breakthrough-therapy-accelerated-approval-priority-review/priority-review

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #1528

              ... om sc dara altså

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1529

                New DARZALEX® (daratumumab) Data from GRIFFIN Study Show High Response Rate and Depth of Response in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant-Eligible https://www.prnewswire.com/news-releases/new-darzalex-daratumumab-data-from-griffin-study-show-high-response-rate-and-depth-of-response-in-patients-with-newly-diagnosed-multiple-myeloma-who-are-transplant-eligible-300918272.html

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1530

                  looks like very good data.to me

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1531

                    it also mentions PLEIADES data has been included in the submission of the SC BLA to the FDA

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1532

                      https://twitter.com/notthatjensmith/status/1172894272238104578

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1533

                        https://twitter.com/theMMRF/status/1173218606643142656

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #1534

                          https://twitter.com/MM_Hub/status/1172866987040677888

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #1535

                            Most impressing is the doubling of MRDneg in Griffin.

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #1536

                              ... more than doubling it is

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                              • P Offline
                                P Offline
                                peter12
                                wrote on sidst redigeret af
                                #1537

                                Lidt bedre end fra Ph1 https://www.targetedonc.com/investigator-perspectives/frontline-mm/the-griffin-trial-in-multiple-myeloma

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                                0
                                • B Offline
                                  B Offline
                                  bibob
                                  wrote on sidst redigeret af
                                  #1538

                                  Dara kan stort set ikke undgå at blive en del af frontline i alle kombi som de parres med. Alt bliver bedre. " vil De have det bedste udkomme. - bare tilsæt Dara. " 😄

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #1539

                                    Det har været nogle gode dage at være Genmab aktionær. Kursen skal nok afspejle fremgangene på et tidspunkt.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1540

                                      Nu er spørgsmålet så om Griffin kommer på compendia listing og dermed kan bruges off label. Der går en rum tid før der ligger Perseus data, der kan files på.

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #1541

                                        Er det ikke mærkeligt at fastsætte et endpoint og statistisk metode til at vurdere forsøget på, hvis ikke der er en ide med det.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #1542

                                          De 41% der fik IRR i Griffin, får vi næste gang beydeligt lavere, da både Perseus og Cepheus kører med sc dara.

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