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Genmab — December 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #678

    Not long ago it was published in some MS-news that Ocrevus might have this issue with loss of vaccinal immunity. I assume that's why Novartis wants to find out whether that goes for ofa as well. Would not be good. Especially if it is also an issue with the corona vaccines.

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #679

      I asked Winkel about it in August, but he didn't answer.

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      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #680

        But evidence shows that some patients given vaccines to protect against the influenza virus or pneumococcal bacteria lose such immunity after Ocrevus treatment. https://multiplesclerosisnewstoday.com/news-posts/2020/08/21/ocrevus-eliminates-vaccine-immunity-to-varicella-zoster-virus-rrms-patient-case-report/

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #681

          It is an issue. We can hope that the way Kesimpta is administered and dose will have less B cell depletion and faster recovery in the case of a pause in treatment; if that is the case Kesimpta would be the preferred drug vs Ocrevus

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #682

            i am sure Novartis is getting a lot of questions about this at the moment and I see the trial above just as much in the light of the covid vaccine as the influenze (as i guess you do)

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            • R Offline
              R Offline
              Rondo
              wrote on sidst redigeret af
              #683

              Ja ja så banker vi på igen igen ....:-)

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #684

                anyone following Novo know more about that new company? Will Mim8 move there for example? Will the Duobody licence move there fully, or will Novo nordisk still have access?

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #685

                  I wonder if it is an issue with weakened virus vaccines only, and not with those based on mRNA?

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #686

                    I can't answer that i am afraid...and i doubt Novartis will be able to do any trials on these vaccines until things settle down and vaccines will be widely available, I think we'll have to do with the influenza as substitute for now...

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #687

                      there will be quit a few drugs that have this issue...

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #688

                        Igen i dag hjalp det på både omsætning og kurs, at usa kom til undsætning.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #689

                          Novo invests in Hemab @endpointsnews https://endpts.com/novo-invests-in-hemab-a-company-going-against-the-hemophilia-gene-therapy-grain-with-a-plan-for-bispecifics/

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                          • D Offline
                            D Offline
                            Doublo
                            wrote on sidst redigeret af
                            #690

                            Jeg har proxy error og kan ikke komme ind på Nordnet, oplever I det samme?

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #691

                              brug det gamle

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                              0
                              • D Offline
                                D Offline
                                Doublo
                                wrote on sidst redigeret af
                                #692

                                hvordan mener du? jeg kan slet ikke komme ind.

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                                • nohopeN Offline
                                  nohopeN Offline
                                  nohope
                                  wrote on sidst redigeret af
                                  #693

                                  Ditto her.

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #694

                                    det gamle nordnet virker

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                                    • A Offline
                                      A Offline
                                      AaBforever
                                      wrote on sidst redigeret af
                                      #695

                                      Jeps.. men problemet er at du kun kan komme på det gamle via det nye.

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                                      • A Offline
                                        A Offline
                                        AaBforever
                                        wrote on sidst redigeret af
                                        #696

                                        Jeg bruger stadig mest det gamle.

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                                        • D Offline
                                          D Offline
                                          Doublo
                                          wrote on sidst redigeret af
                                          #697

                                          Nogen der kan fortælle slut kursen?

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                                          0

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