Genmab — December 2020

[E_L]

• Funded through Novo Seeds' company creation and building efforts

• Focus on rare underserved bleeding disorders with large unmet need

• Brings together a strong industrial R&D team with deep expertise in hemophilia and clinically validated technologies from Novo Nordisk and Genmab A/S

[Vitus]

Utrolig lav omsætning i Genmab....hvad sker der eller hvad sker der ikke ???

[AaBforever]

Der sker det som plejer...business as usual..rollercoaster;.)

[AaBforever]

[gdn55]

Et gæt kunne være at en del spekulanter, skifter Genmab ud med Bavarian Nordich.H
eld og lykke siger jeg bare

[E_L]

A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab https://clinicaltrials.gov/ct2/show/NCT04667117?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody+OR+hexabody+OR+Teclistamab+OR+Amivantamab+OR+Talquetamab+OR+Epcoritamab+OR+DuoHexabody&lupd_s=12%2F12%2F2020&draw=2&rank=1

[Bulder]

Not long ago it was published in some MS-news that Ocrevus might have this issue with loss of vaccinal immunity. I assume that's why Novartis wants to find out whether that goes for ofa as well. Would not be good. Especially if it is also an issue with the corona vaccines.

[Bulder]

I asked Winkel about it in August, but he didn't answer.

[Bulder]

But evidence shows that some patients given vaccines to protect against the influenza virus or pneumococcal bacteria lose such immunity after Ocrevus treatment. https://multiplesclerosisnewstoday.com/news-posts/2020/08/21/ocrevus-eliminates-vaccine-immunity-to-varicella-zoster-virus-rrms-patient-case-report/

[E_L]

It is an issue. We can hope that the way Kesimpta is administered and dose will have less B cell depletion and faster recovery in the case of a pause in treatment; if that is the case Kesimpta would be the preferred drug vs Ocrevus

[E_L]

i am sure Novartis is getting a lot of questions about this at the moment and I see the trial above just as much in the light of the covid vaccine as the influenze (as i guess you do)

[Rondo]

Ja ja så banker vi på igen igen ....:-)

[E_L]

anyone following Novo know more about that new company? Will Mim8 move there for example? Will the Duobody licence move there fully, or will Novo nordisk still have access?

[Bulder]

I wonder if it is an issue with weakened virus vaccines only, and not with those based on mRNA?

[E_L]

I can't answer that i am afraid...and i doubt Novartis will be able to do any trials on these vaccines until things settle down and vaccines will be widely available, I think we'll have to do with the influenza as substitute for now...

[E_L]

there will be quit a few drugs that have this issue...

[Bulder]

Igen i dag hjalp det på både omsætning og kurs, at usa kom til undsætning.

[E_L]

Novo invests in Hemab @endpointsnews https://endpts.com/novo-invests-in-hemab-a-company-going-against-the-hemophilia-gene-therapy-grain-with-a-plan-for-bispecifics/

[Doublo]

Jeg har proxy error og kan ikke komme ind på Nordnet, oplever I det samme?

[Bulder]

brug det gamle