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Genmab — December 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • G Offline
    G Offline
    gdn55
    wrote on sidst redigeret af
    #676

    Et gæt kunne være at en del spekulanter, skifter Genmab ud med Bavarian Nordich.H
    eld og lykke siger jeg bare

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #677

      A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab https://clinicaltrials.gov/ct2/show/NCT04667117?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody+OR+hexabody+OR+Teclistamab+OR+Amivantamab+OR+Talquetamab+OR+Epcoritamab+OR+DuoHexabody&lupd_s=12%2F12%2F2020&draw=2&rank=1

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      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #678

        Not long ago it was published in some MS-news that Ocrevus might have this issue with loss of vaccinal immunity. I assume that's why Novartis wants to find out whether that goes for ofa as well. Would not be good. Especially if it is also an issue with the corona vaccines.

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #679

          I asked Winkel about it in August, but he didn't answer.

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #680

            But evidence shows that some patients given vaccines to protect against the influenza virus or pneumococcal bacteria lose such immunity after Ocrevus treatment. https://multiplesclerosisnewstoday.com/news-posts/2020/08/21/ocrevus-eliminates-vaccine-immunity-to-varicella-zoster-virus-rrms-patient-case-report/

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #681

              It is an issue. We can hope that the way Kesimpta is administered and dose will have less B cell depletion and faster recovery in the case of a pause in treatment; if that is the case Kesimpta would be the preferred drug vs Ocrevus

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #682

                i am sure Novartis is getting a lot of questions about this at the moment and I see the trial above just as much in the light of the covid vaccine as the influenze (as i guess you do)

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                • R Offline
                  R Offline
                  Rondo
                  wrote on sidst redigeret af
                  #683

                  Ja ja så banker vi på igen igen ....:-)

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #684

                    anyone following Novo know more about that new company? Will Mim8 move there for example? Will the Duobody licence move there fully, or will Novo nordisk still have access?

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #685

                      I wonder if it is an issue with weakened virus vaccines only, and not with those based on mRNA?

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #686

                        I can't answer that i am afraid...and i doubt Novartis will be able to do any trials on these vaccines until things settle down and vaccines will be widely available, I think we'll have to do with the influenza as substitute for now...

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #687

                          there will be quit a few drugs that have this issue...

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #688

                            Igen i dag hjalp det på både omsætning og kurs, at usa kom til undsætning.

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #689

                              Novo invests in Hemab @endpointsnews https://endpts.com/novo-invests-in-hemab-a-company-going-against-the-hemophilia-gene-therapy-grain-with-a-plan-for-bispecifics/

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                              • D Offline
                                D Offline
                                Doublo
                                wrote on sidst redigeret af
                                #690

                                Jeg har proxy error og kan ikke komme ind på Nordnet, oplever I det samme?

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #691

                                  brug det gamle

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                                  • D Offline
                                    D Offline
                                    Doublo
                                    wrote on sidst redigeret af
                                    #692

                                    hvordan mener du? jeg kan slet ikke komme ind.

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                                    • nohopeN Offline
                                      nohopeN Offline
                                      nohope
                                      wrote on sidst redigeret af
                                      #693

                                      Ditto her.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #694

                                        det gamle nordnet virker

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                                        • A Offline
                                          A Offline
                                          AaBforever
                                          wrote on sidst redigeret af
                                          #695

                                          Jeps.. men problemet er at du kun kan komme på det gamle via det nye.

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