Genmab — December 2020

[Sukkeralf]

IGM Biosciences (IGM2323 - CD20/CD3 IgM BsAb) was predicted to go down after ASH. Yesterday it went up 16% and today 8% even though they are going for an emission. So probably something to still keep an eye on !

[Sukkeralf]

Maybe even more interesting to follow is IGM8444 that just started in the clinic - its a IgM DR5 antibody.

[Sukkeralf]

Genmab should buy them

[E_L]

maybe there was an even larger emission expected ? I don't get it... smells fishy to me, not buying it lol

[Solsen]

Pæn stigning i dag. Spændende hvad der kommer af info i aften.

[E_L]

do you expect anything?

[Bulder]

Det var jo tydeligvis da us kom på banen, at dagens stigning for alvor begyndte. Så gårsdagens fald i gmab.us fik ingen indflydelse.

[Bulder]

E L maybe a hint on epco-filing

[JørgenVarnæs]

Er der nogle frække fyre med på linien?

[E_L]

[E_L]

Hutchings , the new Plessner, presents epco

[JørgenVarnæs]

2021 and beyond in abt one hour

[JørgenVarnæs]

Epco SC provides opportunity to administer for longer time than IV

[JørgenVarnæs]

Optimal epco dose decided by efficacy - not toxicity

[JørgenVarnæs]

Optimal dose 48mg only has n=12

[JørgenVarnæs]

Epco also uses step-up dosing

[JørgenVarnæs]

Discontinued treatment due to lack of response - not AE

[JørgenVarnæs]

Grade 1 and 2 AE’s only - can be managed in outpatient settings - or at home....

[Solsen]

Super safety må man sige.

[JørgenVarnæs]

Shocking ORR