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Genmab — December 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • P Offline
    P Offline
    Plimsoller
    wrote on sidst redigeret af
    #452

    Thank you E L.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #453

      i have to say i was a bit surprised Hutchings mentioned it, but we look a lot at MM where the bar is set much higher now, with many drugs already working well and long. In this area , if you see patients still at CR after 12 months you are already doing really well i guess . I keep forgetting that.

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #454

        IGM Biosciences (IGM2323 - CD20/CD3 IgM BsAb) was predicted to go down after ASH. Yesterday it went up 16% and today 8% even though they are going for an emission. So probably something to still keep an eye on !

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #455

          Maybe even more interesting to follow is IGM8444 that just started in the clinic - its a IgM DR5 antibody.

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #456

            Genmab should buy them 🙂

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #457

              maybe there was an even larger emission expected ? I don't get it... smells fishy to me, not buying it lol

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #458

                Pæn stigning i dag. Spændende hvad der kommer af info i aften.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #459

                  do you expect anything?

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #460

                    Det var jo tydeligvis da us kom på banen, at dagens stigning for alvor begyndte. Så gårsdagens fald i gmab.us fik ingen indflydelse.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #461

                      E L maybe a hint on epco-filing

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                      • JørgenVarnæsJ Offline
                        JørgenVarnæsJ Offline
                        JørgenVarnæs
                        wrote on sidst redigeret af
                        #462

                        Er der nogle frække fyre med på linien?

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #463

                          😉

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #464

                            Hutchings , the new Plessner, presents epco 😉

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                            • JørgenVarnæsJ Offline
                              JørgenVarnæsJ Offline
                              JørgenVarnæs
                              wrote on sidst redigeret af
                              #465

                              2021 and beyond in abt one hour

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                              • JørgenVarnæsJ Offline
                                JørgenVarnæsJ Offline
                                JørgenVarnæs
                                wrote on sidst redigeret af
                                #466

                                Epco SC provides opportunity to administer for longer time than IV

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                                • JørgenVarnæsJ Offline
                                  JørgenVarnæsJ Offline
                                  JørgenVarnæs
                                  wrote on sidst redigeret af
                                  #467

                                  Optimal epco dose decided by efficacy - not toxicity

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                                  • JørgenVarnæsJ Offline
                                    JørgenVarnæsJ Offline
                                    JørgenVarnæs
                                    wrote on sidst redigeret af
                                    #468

                                    Optimal dose 48mg only has n=12

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                                    • JørgenVarnæsJ Offline
                                      JørgenVarnæsJ Offline
                                      JørgenVarnæs
                                      wrote on sidst redigeret af
                                      #469

                                      Epco also uses step-up dosing

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                                      • JørgenVarnæsJ Offline
                                        JørgenVarnæsJ Offline
                                        JørgenVarnæs
                                        wrote on sidst redigeret af
                                        #470

                                        Discontinued treatment due to lack of response - not AE

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                                        • JørgenVarnæsJ Offline
                                          JørgenVarnæsJ Offline
                                          JørgenVarnæs
                                          wrote on sidst redigeret af
                                          #471

                                          Grade 1 and 2 AE’s only - can be managed in outpatient settings - or at home....

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