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Genmab — December 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #453

    i have to say i was a bit surprised Hutchings mentioned it, but we look a lot at MM where the bar is set much higher now, with many drugs already working well and long. In this area , if you see patients still at CR after 12 months you are already doing really well i guess . I keep forgetting that.

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #454

      IGM Biosciences (IGM2323 - CD20/CD3 IgM BsAb) was predicted to go down after ASH. Yesterday it went up 16% and today 8% even though they are going for an emission. So probably something to still keep an eye on !

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #455

        Maybe even more interesting to follow is IGM8444 that just started in the clinic - its a IgM DR5 antibody.

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #456

          Genmab should buy them 🙂

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #457

            maybe there was an even larger emission expected ? I don't get it... smells fishy to me, not buying it lol

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #458

              Pæn stigning i dag. Spændende hvad der kommer af info i aften.

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #459

                do you expect anything?

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #460

                  Det var jo tydeligvis da us kom på banen, at dagens stigning for alvor begyndte. Så gårsdagens fald i gmab.us fik ingen indflydelse.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #461

                    E L maybe a hint on epco-filing

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                    • JørgenVarnæsJ Offline
                      JørgenVarnæsJ Offline
                      JørgenVarnæs
                      wrote on sidst redigeret af
                      #462

                      Er der nogle frække fyre med på linien?

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #463

                        😉

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #464

                          Hutchings , the new Plessner, presents epco 😉

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                          • JørgenVarnæsJ Offline
                            JørgenVarnæsJ Offline
                            JørgenVarnæs
                            wrote on sidst redigeret af
                            #465

                            2021 and beyond in abt one hour

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                            • JørgenVarnæsJ Offline
                              JørgenVarnæsJ Offline
                              JørgenVarnæs
                              wrote on sidst redigeret af
                              #466

                              Epco SC provides opportunity to administer for longer time than IV

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                              • JørgenVarnæsJ Offline
                                JørgenVarnæsJ Offline
                                JørgenVarnæs
                                wrote on sidst redigeret af
                                #467

                                Optimal epco dose decided by efficacy - not toxicity

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                                • JørgenVarnæsJ Offline
                                  JørgenVarnæsJ Offline
                                  JørgenVarnæs
                                  wrote on sidst redigeret af
                                  #468

                                  Optimal dose 48mg only has n=12

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                                  • JørgenVarnæsJ Offline
                                    JørgenVarnæsJ Offline
                                    JørgenVarnæs
                                    wrote on sidst redigeret af
                                    #469

                                    Epco also uses step-up dosing

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                                    • JørgenVarnæsJ Offline
                                      JørgenVarnæsJ Offline
                                      JørgenVarnæs
                                      wrote on sidst redigeret af
                                      #470

                                      Discontinued treatment due to lack of response - not AE

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                                      • JørgenVarnæsJ Offline
                                        JørgenVarnæsJ Offline
                                        JørgenVarnæs
                                        wrote on sidst redigeret af
                                        #471

                                        Grade 1 and 2 AE’s only - can be managed in outpatient settings - or at home....

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #472

                                          Super safety må man sige.

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