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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #467

    ok. we know Mayo has a Dara trial in CLL, in combination with Ibrutinib, will be interesting to see

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #468

      Could be RA. Has been discussed before. I think Janssen has an unused IND for dara in RA. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932888/

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #469

        https://twitter.com/TiansterZhang/status/1308023977483227137 Amgen showing bispecific CD3x PSMA , like JNJ-63898081

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        • G Offline
          G Offline
          GeorgeBest
          wrote on sidst redigeret af
          #470

          Genmab and Seattle Genetics Present Data from Tisotumab Vedotin
          innovaTV 204 Pivotal Trial in Recurrent or Metastatic Cervical Cancer at
          ESMO Virtual Congress 2020

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          • G Offline
            G Offline
            GeorgeBest
            wrote on sidst redigeret af
            #471

            https://ir.genmab.com/news-releases/news-release-details/genmab-announces-janssen-has-submitted-supplemental-biologics

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #472

              The results of the tisotumab vedotin phase 2 clinical trial are encouraging as they demonstrate clinically meaningful, durable responses with a manageable side effect profile

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #473

                correction for the link GB https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-present-data-tisotumab-vedotin

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                • G Offline
                  G Offline
                  GeorgeBest
                  wrote on sidst redigeret af
                  #474

                  thanks E L

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                  • M Offline
                    M Offline
                    Macabo
                    wrote on sidst redigeret af
                    #475

                    ORR 24% og DOR 8,3 måneder - det er godt men ikke knock of socks niveau

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                    • G Offline
                      G Offline
                      GeorgeBest
                      wrote on sidst redigeret af
                      #476

                      der var ikke forventet mere for tiso

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                      • B Offline
                        B Offline
                        bikube
                        wrote on sidst redigeret af
                        #477

                        Det er da det man forstår ved "late breaking".

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                        • Don_JoningD Offline
                          Don_JoningD Offline
                          Don_Joning
                          wrote on sidst redigeret af
                          #478

                          nogen der har nogen bud på hvor værdifuldt tiso i cervical cancer kan blive?

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #479

                            knock your socks off data er mere relateret til epcoritamab og PD-L1x4-1BB

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                            • G Offline
                              G Offline
                              GeorgeBest
                              wrote on sidst redigeret af
                              #480

                              Tiso: jeg har set estimater på et topsalg på 750M USD i cervical cancer

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #481

                                årligt topsalg

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                                • Don_JoningD Offline
                                  Don_JoningD Offline
                                  Don_Joning
                                  wrote on sidst redigeret af
                                  #482

                                  tak GB det er da alligevel også lidt...

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #483

                                    skal også deles med SGEN

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                                    • Don_JoningD Offline
                                      Don_JoningD Offline
                                      Don_Joning
                                      wrote on sidst redigeret af
                                      #484

                                      ja, men er det ikke 50/50

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                                      • G Offline
                                        G Offline
                                        GeorgeBest
                                        wrote on sidst redigeret af
                                        #485

                                        jo

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                                        • G Offline
                                          G Offline
                                          GeorgeBest
                                          wrote on sidst redigeret af
                                          #486

                                          men tiso kan måske også bruges i andre cancer former. der skulle også komme data på det i år

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                                          0

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