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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #469

    https://twitter.com/TiansterZhang/status/1308023977483227137 Amgen showing bispecific CD3x PSMA , like JNJ-63898081

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    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #470

      Genmab and Seattle Genetics Present Data from Tisotumab Vedotin
      innovaTV 204 Pivotal Trial in Recurrent or Metastatic Cervical Cancer at
      ESMO Virtual Congress 2020

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #471

        https://ir.genmab.com/news-releases/news-release-details/genmab-announces-janssen-has-submitted-supplemental-biologics

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        • G Offline
          G Offline
          GeorgeBest
          wrote on sidst redigeret af
          #472

          The results of the tisotumab vedotin phase 2 clinical trial are encouraging as they demonstrate clinically meaningful, durable responses with a manageable side effect profile

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #473

            correction for the link GB https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-present-data-tisotumab-vedotin

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #474

              thanks E L

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              • M Offline
                M Offline
                Macabo
                wrote on sidst redigeret af
                #475

                ORR 24% og DOR 8,3 måneder - det er godt men ikke knock of socks niveau

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                • G Offline
                  G Offline
                  GeorgeBest
                  wrote on sidst redigeret af
                  #476

                  der var ikke forventet mere for tiso

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                  • B Offline
                    B Offline
                    bikube
                    wrote on sidst redigeret af
                    #477

                    Det er da det man forstår ved "late breaking".

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                    • Don_JoningD Offline
                      Don_JoningD Offline
                      Don_Joning
                      wrote on sidst redigeret af
                      #478

                      nogen der har nogen bud på hvor værdifuldt tiso i cervical cancer kan blive?

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                      • G Offline
                        G Offline
                        GeorgeBest
                        wrote on sidst redigeret af
                        #479

                        knock your socks off data er mere relateret til epcoritamab og PD-L1x4-1BB

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                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #480

                          Tiso: jeg har set estimater på et topsalg på 750M USD i cervical cancer

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #481

                            årligt topsalg

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                            • Don_JoningD Offline
                              Don_JoningD Offline
                              Don_Joning
                              wrote on sidst redigeret af
                              #482

                              tak GB det er da alligevel også lidt...

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #483

                                skal også deles med SGEN

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                                • Don_JoningD Offline
                                  Don_JoningD Offline
                                  Don_Joning
                                  wrote on sidst redigeret af
                                  #484

                                  ja, men er det ikke 50/50

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #485

                                    jo

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                                    • G Offline
                                      G Offline
                                      GeorgeBest
                                      wrote on sidst redigeret af
                                      #486

                                      men tiso kan måske også bruges i andre cancer former. der skulle også komme data på det i år

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #487

                                        fiercebiotech - ESMO: Seattle Genetics' ADC candidate curbs hard-to-treat cervical cancer - https://www.fiercebiotech.com/biotech/esmo-seattle-genetics-adc-curbs-hard-to-treat-cervical-cancer

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                                        • Don_JoningD Offline
                                          Don_JoningD Offline
                                          Don_Joning
                                          wrote on sidst redigeret af
                                          #488

                                          Det giver jo alt sammen til at lave en robust forretning, med mange ben at stå på og det er jo ikke det nemmeste i verden de udvikler på - det kunne også have været et hard stop uden signifikant effekt og 0 værdi i det område.

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