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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #468

    Could be RA. Has been discussed before. I think Janssen has an unused IND for dara in RA. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932888/

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #469

      https://twitter.com/TiansterZhang/status/1308023977483227137 Amgen showing bispecific CD3x PSMA , like JNJ-63898081

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #470

        Genmab and Seattle Genetics Present Data from Tisotumab Vedotin
        innovaTV 204 Pivotal Trial in Recurrent or Metastatic Cervical Cancer at
        ESMO Virtual Congress 2020

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        • G Offline
          G Offline
          GeorgeBest
          wrote on sidst redigeret af
          #471

          https://ir.genmab.com/news-releases/news-release-details/genmab-announces-janssen-has-submitted-supplemental-biologics

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          • G Offline
            G Offline
            GeorgeBest
            wrote on sidst redigeret af
            #472

            The results of the tisotumab vedotin phase 2 clinical trial are encouraging as they demonstrate clinically meaningful, durable responses with a manageable side effect profile

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #473

              correction for the link GB https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-present-data-tisotumab-vedotin

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              • G Offline
                G Offline
                GeorgeBest
                wrote on sidst redigeret af
                #474

                thanks E L

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                • M Offline
                  M Offline
                  Macabo
                  wrote on sidst redigeret af
                  #475

                  ORR 24% og DOR 8,3 måneder - det er godt men ikke knock of socks niveau

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                  • G Offline
                    G Offline
                    GeorgeBest
                    wrote on sidst redigeret af
                    #476

                    der var ikke forventet mere for tiso

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                    • B Offline
                      B Offline
                      bikube
                      wrote on sidst redigeret af
                      #477

                      Det er da det man forstår ved "late breaking".

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                      • Don_JoningD Offline
                        Don_JoningD Offline
                        Don_Joning
                        wrote on sidst redigeret af
                        #478

                        nogen der har nogen bud på hvor værdifuldt tiso i cervical cancer kan blive?

                        1 Reply Last reply
                        0
                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #479

                          knock your socks off data er mere relateret til epcoritamab og PD-L1x4-1BB

                          1 Reply Last reply
                          0
                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #480

                            Tiso: jeg har set estimater på et topsalg på 750M USD i cervical cancer

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                            • G Offline
                              G Offline
                              GeorgeBest
                              wrote on sidst redigeret af
                              #481

                              årligt topsalg

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                              • Don_JoningD Offline
                                Don_JoningD Offline
                                Don_Joning
                                wrote on sidst redigeret af
                                #482

                                tak GB det er da alligevel også lidt...

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                                • G Offline
                                  G Offline
                                  GeorgeBest
                                  wrote on sidst redigeret af
                                  #483

                                  skal også deles med SGEN

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                                  • Don_JoningD Offline
                                    Don_JoningD Offline
                                    Don_Joning
                                    wrote on sidst redigeret af
                                    #484

                                    ja, men er det ikke 50/50

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                                    • G Offline
                                      G Offline
                                      GeorgeBest
                                      wrote on sidst redigeret af
                                      #485

                                      jo

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                                      • G Offline
                                        G Offline
                                        GeorgeBest
                                        wrote on sidst redigeret af
                                        #486

                                        men tiso kan måske også bruges i andre cancer former. der skulle også komme data på det i år

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #487

                                          fiercebiotech - ESMO: Seattle Genetics' ADC candidate curbs hard-to-treat cervical cancer - https://www.fiercebiotech.com/biotech/esmo-seattle-genetics-adc-curbs-hard-to-treat-cervical-cancer

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