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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #458

    @Darvin for Mayo to start a trial is definately news. Really curious if it will be only for Lupus or also for other autoimmune diseases? The NEJM article attracted a surprisingly large number of positive comments from MDs on twitter over the last few days.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #459

      ESMO: Janssen’s anti-EGFR combo tackles lung cancer ahead of phase 3 Tagrisso showdown https://www.fiercebiotech.com/biotech/esmo-janssen-s-anti-egfr-combo-tackles-lung-cancer-ahead-phase-3-tagrisso-showdown

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      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #460

        "The treatment beat back cancer in 20 newly diagnosed, never-before-treated patients, shrinking tumors in all of them. And in 45 patients whose disease had worsened despite taking Tagrisso, J&J’s treatment curbed tumor growth in 60% of them and shrank tumors in 36% of them. One patient had a complete response, meaning the drug eliminated all signs of cancer".

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        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #461

          Tak transalp og Pensionist:-)

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #462

            Styrken er i top: https://www.proinvestor.com/investornyt/667040/6-c25-aktier-scorer-over-55-pa-styrkebarometer-genmab-i-top-58

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #463

              ATH

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              • Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktør
                wrote on sidst redigeret af
                #464

                🙂

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                • DarvinD Offline
                  DarvinD Offline
                  Darvin
                  wrote on sidst redigeret af
                  #465

                  Tillykke og godt gået Helge 😄

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                  • DarvinD Offline
                    DarvinD Offline
                    Darvin
                    wrote on sidst redigeret af
                    #466

                    EL It was Rajkumar who announced It yesterday. And - depending on how you read the text - I read it as if they will open a trial for various autoimmune diseases - but only my way to read it

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #467

                      ok. we know Mayo has a Dara trial in CLL, in combination with Ibrutinib, will be interesting to see

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #468

                        Could be RA. Has been discussed before. I think Janssen has an unused IND for dara in RA. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932888/

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #469

                          https://twitter.com/TiansterZhang/status/1308023977483227137 Amgen showing bispecific CD3x PSMA , like JNJ-63898081

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #470

                            Genmab and Seattle Genetics Present Data from Tisotumab Vedotin
                            innovaTV 204 Pivotal Trial in Recurrent or Metastatic Cervical Cancer at
                            ESMO Virtual Congress 2020

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                            • G Offline
                              G Offline
                              GeorgeBest
                              wrote on sidst redigeret af
                              #471

                              https://ir.genmab.com/news-releases/news-release-details/genmab-announces-janssen-has-submitted-supplemental-biologics

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #472

                                The results of the tisotumab vedotin phase 2 clinical trial are encouraging as they demonstrate clinically meaningful, durable responses with a manageable side effect profile

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #473

                                  correction for the link GB https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-present-data-tisotumab-vedotin

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #474

                                    thanks E L

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                                    • M Offline
                                      M Offline
                                      Macabo
                                      wrote on sidst redigeret af
                                      #475

                                      ORR 24% og DOR 8,3 måneder - det er godt men ikke knock of socks niveau

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                                      • G Offline
                                        G Offline
                                        GeorgeBest
                                        wrote on sidst redigeret af
                                        #476

                                        der var ikke forventet mere for tiso

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                                        • B Offline
                                          B Offline
                                          bikube
                                          wrote on sidst redigeret af
                                          #477

                                          Det er da det man forstår ved "late breaking".

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