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Genmab — September 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #455

    Onc.live : Amivantamab https://www.onclive.com/view/egfr-met-bispecific-antibody-amivantamab-excels-in-advanced-egfr-mutant-nsclc?eKey=amFuYm9ydXAxOTc4QGdtYWlsLmNvbQ==

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #456

      2 more twitter threads on Amivantamab, Stephen V Liu https://twitter.com/StephenVLiu/status/1307692420528832513 and Joshua Bauml https://twitter.com/Jbauml/status/1307839573435781120

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #457

        and since nobody bothered to correct my comment from yesterday evening (even thought i am sure you had all seen the mistake) ; i meant 2 Ph III trials for Amivantamab

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #458

          @Darvin for Mayo to start a trial is definately news. Really curious if it will be only for Lupus or also for other autoimmune diseases? The NEJM article attracted a surprisingly large number of positive comments from MDs on twitter over the last few days.

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #459

            ESMO: Janssen’s anti-EGFR combo tackles lung cancer ahead of phase 3 Tagrisso showdown https://www.fiercebiotech.com/biotech/esmo-janssen-s-anti-egfr-combo-tackles-lung-cancer-ahead-phase-3-tagrisso-showdown

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            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #460

              "The treatment beat back cancer in 20 newly diagnosed, never-before-treated patients, shrinking tumors in all of them. And in 45 patients whose disease had worsened despite taking Tagrisso, J&J’s treatment curbed tumor growth in 60% of them and shrank tumors in 36% of them. One patient had a complete response, meaning the drug eliminated all signs of cancer".

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              • Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktør
                wrote on sidst redigeret af
                #461

                Tak transalp og Pensionist:-)

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                • Helge_LarsenPI-redaktørH Offline
                  Helge_LarsenPI-redaktørH Offline
                  Helge_LarsenPI-redaktør
                  wrote on sidst redigeret af
                  #462

                  Styrken er i top: https://www.proinvestor.com/investornyt/667040/6-c25-aktier-scorer-over-55-pa-styrkebarometer-genmab-i-top-58

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #463

                    ATH

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                    • Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktør
                      wrote on sidst redigeret af
                      #464

                      🙂

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                      • DarvinD Offline
                        DarvinD Offline
                        Darvin
                        wrote on sidst redigeret af
                        #465

                        Tillykke og godt gået Helge 😄

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                        • DarvinD Offline
                          DarvinD Offline
                          Darvin
                          wrote on sidst redigeret af
                          #466

                          EL It was Rajkumar who announced It yesterday. And - depending on how you read the text - I read it as if they will open a trial for various autoimmune diseases - but only my way to read it

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #467

                            ok. we know Mayo has a Dara trial in CLL, in combination with Ibrutinib, will be interesting to see

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #468

                              Could be RA. Has been discussed before. I think Janssen has an unused IND for dara in RA. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932888/

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #469

                                https://twitter.com/TiansterZhang/status/1308023977483227137 Amgen showing bispecific CD3x PSMA , like JNJ-63898081

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                                • G Offline
                                  G Offline
                                  GeorgeBest
                                  wrote on sidst redigeret af
                                  #470

                                  Genmab and Seattle Genetics Present Data from Tisotumab Vedotin
                                  innovaTV 204 Pivotal Trial in Recurrent or Metastatic Cervical Cancer at
                                  ESMO Virtual Congress 2020

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #471

                                    https://ir.genmab.com/news-releases/news-release-details/genmab-announces-janssen-has-submitted-supplemental-biologics

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                                    • G Offline
                                      G Offline
                                      GeorgeBest
                                      wrote on sidst redigeret af
                                      #472

                                      The results of the tisotumab vedotin phase 2 clinical trial are encouraging as they demonstrate clinically meaningful, durable responses with a manageable side effect profile

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #473

                                        correction for the link GB https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-present-data-tisotumab-vedotin

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                                        • G Offline
                                          G Offline
                                          GeorgeBest
                                          wrote on sidst redigeret af
                                          #474

                                          thanks E L

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