Genmab — Maj 2020
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4544 / 12 - Multifaceted mechanism of action of DuoHexaBody-CD37 involves both complement- and Fc gamma receptor-mediated cytotoxicity in pre-clinical B-cell lymphoma models https://www.abstractsonline.com/pp8/#!/9045/presentation/7694
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JNJ-61186372, an EGFR-cMet bispecific antibody, in EGFR Exon 20 insertion-driven advanced non-small cell lung cancer (NSCLC) https://www.abstractsonline.com/pp8/#!/9045/presentation/5116
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JNJ-61186372, an Fc enhanced EGFR/cMet bispecific antibody, mediates EGFR and cMet downmodulation and therapeutic efficacy preclinically through monocyte / macrophage mediated trogocytosis https://www.abstractsonline.com/pp8/#!/9045/presentation/7722
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JNJ-67571244: A novel anti-CD33 C2 domain binding bispecific antibody with potent T cell redirection activity https://www.abstractsonline.com/pp8/#!/9045/presentation/7733
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a few abstracts on BMS-986253
at ASCO (talking about something where i think there is not much to look forward to lol) -
@Mohty_EBMT
presented an argument FOR the integration of anti-CD38 antibodies into induction therapies. https://twitter.com/MM_Hub/status/1261257388159635456 -
Educational theme | Monoclonal antibodies for the treatment of multiple myeloma https://multiplemyelomahub.com/medical-information/educational-theme-monoclonal-antibodies-for-the-treatment-of-multiple-myeloma
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https://www.fiercebiotech.com/biotech/what-pandemic-adc-s-233m-listing-biotech-ipos-keep-rolling this has a bit more on Cami
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Fandt nedenståen i securities filingen fra ADC - ikke uinteressant vist, der blev talt om det herinde for nylig (GENs mulighed for at forhandle de 25%). https://www.sec.gov/Archives/edgar/data/1771910/000114036120009738/nt10009045x3_f1.htm
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"Risks Related to Our Relationship with Third Parties / Our rights to Cami are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will maintain the rights to develop or commercialize Cami. / Our collaboration and license agreement with Genmab requires a divestment of Cami, in which Genmab has a 25% interest, following 60 days, and no later than 65 days, after the database lock for the Phase 1/2 clinical trial, which occurred on April 2, 2020."
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