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Genmab — Maj 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #1250

    Its funny they promote these newer DuoBodies - not much we hear about JNJ-63709178. 1 or 2 clinical holds so maybe not much to look forward to here

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1251

      they did double the enrollment size not too long ago though on the -178 , that actually gave me little bit more hope 😉

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      • E Offline
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        E_L
        wrote on sidst redigeret af
        #1252

        a few abstracts on BMS-986253
        at ASCO (talking about something where i think there is not much to look forward to lol)

        https://meetinglibrary.asco.org/results/986253?page=1

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        • E Offline
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          E_L
          wrote on sidst redigeret af
          #1253

          @Mohty_EBMT
          presented an argument FOR the integration of anti-CD38 antibodies into induction therapies. https://twitter.com/MM_Hub/status/1261257388159635456

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          • S Offline
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            Sukkeralf
            wrote on sidst redigeret af
            #1254

            CD20/CD3 - måske postet før:

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            • S Offline
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              Sukkeralf
              wrote on sidst redigeret af
              #1255

              Link Preview Image
              Bispecific Antibodies Poised to Impact Treatment of Lymphoma and Other Blood Cancers

              favicon

              (www.ascopost.com)

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1256

                Tak sukker. Rart med samling på tingene 🙂

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                • E Offline
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                  E_L
                  wrote on sidst redigeret af
                  #1257

                  Educational theme | Monoclonal antibodies for the treatment of multiple myeloma https://multiplemyelomahub.com/medical-information/educational-theme-monoclonal-antibodies-for-the-treatment-of-multiple-myeloma

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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #1258

                    ADCs IPO i $19 https://finance.yahoo.com/m/aa62ce39-db78-3b7c-9bda-53e4c6e4d971/adc-therapeutics-prices-ipo.html

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                    • E Offline
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                      E_L
                      wrote on sidst redigeret af
                      #1259

                      https://www.fiercebiotech.com/biotech/what-pandemic-adc-s-233m-listing-biotech-ipos-keep-rolling this has a bit more on Cami

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                      • K Offline
                        K Offline
                        kkjoel
                        wrote on sidst redigeret af
                        #1260

                        Tak EL. Rart med opsummering af mAb feltet/stofferne indenfor MM.. for os der ikke er helt stive i det hele 🙂

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                        • K Offline
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                          kkjoel
                          wrote on sidst redigeret af
                          #1261

                          Fandt nedenståen i securities filingen fra ADC - ikke uinteressant vist, der blev talt om det herinde for nylig (GENs mulighed for at forhandle de 25%). https://www.sec.gov/Archives/edgar/data/1771910/000114036120009738/nt10009045x3_f1.htm

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                          • K Offline
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                            kkjoel
                            wrote on sidst redigeret af
                            #1262

                            "Risks Related to Our Relationship with Third Parties / Our rights to Cami are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will maintain the rights to develop or commercialize Cami. / Our collaboration and license agreement with Genmab requires a divestment of Cami, in which Genmab has a 25% interest, following 60 days, and no later than 65 days, after the database lock for the Phase 1/2 clinical trial, which occurred on April 2, 2020."

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                            • K Offline
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                              kkjoel
                              wrote on sidst redigeret af
                              #1263

                              "See “Business—License and Collaboration Agreements—Genmab Collaboration and License Agreement.” The agreement sets out a defined process to facilitate the divestment of Cami by licensing the rights thereto to a third party, subject to Genmab’s right of first opportunity to negotiate to acquire Cami in full. This process includes the opportunity for both parties to bid for the license rights alongside third parties."

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                              • K Offline
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                                kkjoel
                                wrote on sidst redigeret af
                                #1264

                                "Both parties are required to use commercially reasonable efforts to complete and maximize the value obtained in this process. Therefore, our rights to Cami are subject to our collaboration and license agreement with Genmab, and there can be no assurance that we will apply for regulatory approval of or commercialize Cami."

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                                • K Offline
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                                  kkjoel
                                  wrote on sidst redigeret af
                                  #1265
                                  1. forekomst af "Business—License and Collaboration Agreements—Genmab Collaboration and License Agreement"
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                                  • K Offline
                                    K Offline
                                    kkjoel
                                    wrote on sidst redigeret af
                                    #1266

                                    Så gad vide om der SKAL forhandles indenfor de 65 dg fra 02.04, eller om det "partial clinical hold" (omtalt i Fiercebiotech artilen EL linkede til 17:15)
                                    gør at det hele udskydes?!

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                                    • K Offline
                                      K Offline
                                      kkjoel
                                      wrote on sidst redigeret af
                                      #1267
                                      1. forekomst...
                                        henviste til at interesserede selv kunne fremsøge i nævnte securities filing.
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                                      • K Offline
                                        K Offline
                                        kkjoel
                                        wrote on sidst redigeret af
                                        #1268

                                        I hvert fald vel interessant at GEN har kontraktsikret førsteret for at forhandle cami 100% hjem igen. Nogen der kan sige noget om hvor normal og/eller dyrt det måtte være?

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                                        • K Offline
                                          K Offline
                                          kkjoel
                                          wrote on sidst redigeret af
                                          #1269

                                          Hvis data er gode.. kunne det måske være en fornuftig måde at bruge noget af formuen på?!

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