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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • G Offline
    G Offline
    gentogen
    wrote on sidst redigeret af
    #777

    In the article (looks absolutely great) they also have a reference to this one; "CD20 And CD37 Antibodies Synergize To Activate Complement By Fc-Mediated Clustering". It also looks very promising: http://www.haematologica.org/content/104/9/1841

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #778

      By the way, it looks like the first author Simone Oostindie is not only at Genmab but also works at the same place as Paul Parren

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #779

        it is a University Medical Centre, in Leiden. Parren is a Professor there, maybe she is doing her Phd with him there

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #780

          Usmani starts a small trial of Dara-Pembro for Heavily pre-treated Multiple Myeloma Patients https://clinicaltrials.gov/ct2/show/NCT04361851?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody&lupd_s=04%2F28%2F2020&draw=2&rank=5

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #781

            En detalje fra artikel: We speculate that combinations of DuoHexaBody-CD37 with pro-apoptotic PI3K-δ-inhibitors such as idelalisib may work synergistically,

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #782

              No doubt that CD37 could be huge. I have seen many articles about the synergy with CD20 but also CD37 alone. http://www.haematologica.org/content/104/9/1841 https://ashpublications.org/blood/article/132/Supplement 1/4170/275811/DuohexabodyCD37-a-Novel-Bispecific-Antibody-with-a and yes perhaps included in the bag in the coming partnerdeal.

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              • Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktør
                wrote on sidst redigeret af
                #783

                Just a moment...

                favicon

                (www.proinvestor.com)

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #784

                  Novartis AG (NVS) CEO on Q1 2020 Results - Earnings Call Transcript https://seekingalpha.com/article/4340622-novartis-ag-nvs-ceo-vasant-narasimhan-on-q1-2020-results-earnings-call-transcript?part=single

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #785

                    quite a few comments/ questions on ofatumumab

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                    • G Offline
                      G Offline
                      GeorgeBest
                      wrote on sidst redigeret af
                      #786

                      Sounds like Novartis will be very aggressive in maketing ofa in MS...

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                      • T Offline
                        T Offline
                        transalp
                        wrote on sidst redigeret af
                        #787

                        Go morgen.. 🙂

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                        • B Offline
                          B Offline
                          bibob
                          wrote on sidst redigeret af
                          #788

                          God morgen. 🙂

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                          • H Offline
                            H Offline
                            Hamming
                            wrote on sidst redigeret af
                            #789

                            Link Preview Image
                            PharmiWeb.com – Thank you

                            After twenty-five years, PharmiWeb.com is closing. A note of thanks to the pharmaceutical industry community that built it.

                            favicon

                            (www.pharmiweb.com)

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                            • H Offline
                              H Offline
                              Hamming
                              wrote on sidst redigeret af
                              #790

                              Enapotamab er "
                              next up"

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                              • P Offline
                                P Offline
                                Parasitism
                                wrote on sidst redigeret af
                                #791

                                God morgen 🙂

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                                • B Offline
                                  B Offline
                                  bibob
                                  wrote on sidst redigeret af
                                  #792

                                  @Hamming. Dit link er til Bemcentinib. ??

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                                  • H Offline
                                    H Offline
                                    Hamming
                                    wrote on sidst redigeret af
                                    #793

                                    Bemcentinibs target er AXL = det samme som Enapotamab

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #794

                                      Ja,okay. Men det betyder jo ikke at Ena. også vil blive testet . !!??

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                                      • H Offline
                                        H Offline
                                        Hamming
                                        wrote on sidst redigeret af
                                        #795

                                        Selvfølgelig ikke

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                                        0
                                        • H Offline
                                          H Offline
                                          Hamming
                                          wrote on sidst redigeret af
                                          #796

                                          Men interessant at se, hvor mange forskellige targets og tilgange der bliver bragt i anvendelse ift Covid. Og så kan man jo altid drømme om at Genmab kunne bidrage med et relevant stof....

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