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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #774

    My preferred partner would be Novartis or Janssen at the moment

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #775

      i think we could all be happy with those

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      • troldmandenT Offline
        troldmandenT Offline
        troldmanden
        wrote on sidst redigeret af
        #776

        Helst ikke JnJ. Ikke for mange store æg i samme kurv....

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #777

          In the article (looks absolutely great) they also have a reference to this one; "CD20 And CD37 Antibodies Synergize To Activate Complement By Fc-Mediated Clustering". It also looks very promising: http://www.haematologica.org/content/104/9/1841

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #778

            By the way, it looks like the first author Simone Oostindie is not only at Genmab but also works at the same place as Paul Parren

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #779

              it is a University Medical Centre, in Leiden. Parren is a Professor there, maybe she is doing her Phd with him there

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #780

                Usmani starts a small trial of Dara-Pembro for Heavily pre-treated Multiple Myeloma Patients https://clinicaltrials.gov/ct2/show/NCT04361851?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody&lupd_s=04%2F28%2F2020&draw=2&rank=5

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                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #781

                  En detalje fra artikel: We speculate that combinations of DuoHexaBody-CD37 with pro-apoptotic PI3K-δ-inhibitors such as idelalisib may work synergistically,

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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #782

                    No doubt that CD37 could be huge. I have seen many articles about the synergy with CD20 but also CD37 alone. http://www.haematologica.org/content/104/9/1841 https://ashpublications.org/blood/article/132/Supplement 1/4170/275811/DuohexabodyCD37-a-Novel-Bispecific-Antibody-with-a and yes perhaps included in the bag in the coming partnerdeal.

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                    • Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktør
                      wrote on sidst redigeret af
                      #783

                      Just a moment...

                      favicon

                      (www.proinvestor.com)

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #784

                        Novartis AG (NVS) CEO on Q1 2020 Results - Earnings Call Transcript https://seekingalpha.com/article/4340622-novartis-ag-nvs-ceo-vasant-narasimhan-on-q1-2020-results-earnings-call-transcript?part=single

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #785

                          quite a few comments/ questions on ofatumumab

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #786

                            Sounds like Novartis will be very aggressive in maketing ofa in MS...

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                            • T Offline
                              T Offline
                              transalp
                              wrote on sidst redigeret af
                              #787

                              Go morgen.. 🙂

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                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #788

                                God morgen. 🙂

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                                • H Offline
                                  H Offline
                                  Hamming
                                  wrote on sidst redigeret af
                                  #789

                                  Link Preview Image
                                  PharmiWeb.com – Thank you

                                  After twenty-five years, PharmiWeb.com is closing. A note of thanks to the pharmaceutical industry community that built it.

                                  favicon

                                  (www.pharmiweb.com)

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                                  • H Offline
                                    H Offline
                                    Hamming
                                    wrote on sidst redigeret af
                                    #790

                                    Enapotamab er "
                                    next up"

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                                    • P Offline
                                      P Offline
                                      Parasitism
                                      wrote on sidst redigeret af
                                      #791

                                      God morgen 🙂

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                                      • B Offline
                                        B Offline
                                        bibob
                                        wrote on sidst redigeret af
                                        #792

                                        @Hamming. Dit link er til Bemcentinib. ??

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                                        • H Offline
                                          H Offline
                                          Hamming
                                          wrote on sidst redigeret af
                                          #793

                                          Bemcentinibs target er AXL = det samme som Enapotamab

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                                          0

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