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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #775

    i think we could all be happy with those

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    • troldmandenT Offline
      troldmandenT Offline
      troldmanden
      wrote on sidst redigeret af
      #776

      Helst ikke JnJ. Ikke for mange store æg i samme kurv....

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #777

        In the article (looks absolutely great) they also have a reference to this one; "CD20 And CD37 Antibodies Synergize To Activate Complement By Fc-Mediated Clustering". It also looks very promising: http://www.haematologica.org/content/104/9/1841

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #778

          By the way, it looks like the first author Simone Oostindie is not only at Genmab but also works at the same place as Paul Parren

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #779

            it is a University Medical Centre, in Leiden. Parren is a Professor there, maybe she is doing her Phd with him there

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #780

              Usmani starts a small trial of Dara-Pembro for Heavily pre-treated Multiple Myeloma Patients https://clinicaltrials.gov/ct2/show/NCT04361851?term=genmab+OR+daratumumab+OR+darzalex+OR+ofatumumab+OR+Teprotumumab+OR+Tisotumab+OR+camidanlumab+OR+Enapotamab+OR+ADCT-301+OR+duobody&lupd_s=04%2F28%2F2020&draw=2&rank=5

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              • G Offline
                G Offline
                gentogen
                wrote on sidst redigeret af
                #781

                En detalje fra artikel: We speculate that combinations of DuoHexaBody-CD37 with pro-apoptotic PI3K-δ-inhibitors such as idelalisib may work synergistically,

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #782

                  No doubt that CD37 could be huge. I have seen many articles about the synergy with CD20 but also CD37 alone. http://www.haematologica.org/content/104/9/1841 https://ashpublications.org/blood/article/132/Supplement 1/4170/275811/DuohexabodyCD37-a-Novel-Bispecific-Antibody-with-a and yes perhaps included in the bag in the coming partnerdeal.

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                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #783

                    Just a moment...

                    favicon

                    (www.proinvestor.com)

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #784

                      Novartis AG (NVS) CEO on Q1 2020 Results - Earnings Call Transcript https://seekingalpha.com/article/4340622-novartis-ag-nvs-ceo-vasant-narasimhan-on-q1-2020-results-earnings-call-transcript?part=single

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #785

                        quite a few comments/ questions on ofatumumab

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                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #786

                          Sounds like Novartis will be very aggressive in maketing ofa in MS...

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                          • T Offline
                            T Offline
                            transalp
                            wrote on sidst redigeret af
                            #787

                            Go morgen.. 🙂

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                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #788

                              God morgen. 🙂

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                              • H Offline
                                H Offline
                                Hamming
                                wrote on sidst redigeret af
                                #789

                                Link Preview Image
                                PharmiWeb.com – Thank you

                                After twenty-five years, PharmiWeb.com is closing. A note of thanks to the pharmaceutical industry community that built it.

                                favicon

                                (www.pharmiweb.com)

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                                • H Offline
                                  H Offline
                                  Hamming
                                  wrote on sidst redigeret af
                                  #790

                                  Enapotamab er "
                                  next up"

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                                  • P Offline
                                    P Offline
                                    Parasitism
                                    wrote on sidst redigeret af
                                    #791

                                    God morgen 🙂

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #792

                                      @Hamming. Dit link er til Bemcentinib. ??

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                                      • H Offline
                                        H Offline
                                        Hamming
                                        wrote on sidst redigeret af
                                        #793

                                        Bemcentinibs target er AXL = det samme som Enapotamab

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                                        • B Offline
                                          B Offline
                                          bibob
                                          wrote on sidst redigeret af
                                          #794

                                          Ja,okay. Men det betyder jo ikke at Ena. også vil blive testet . !!??

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