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Genmab — Juli 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #2149

    this smoldering SC trial seems fully recruited https://www.clinicaltrials.gov/ct2/history/NCT03301220?A=21&B=22&C=merged#StudyPageTop

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #2150

      Columba reached Primary Completion Date - as expected https://www.clinicaltrials.gov/ct2/history/NCT03277105?A=24&B=25&C=merged#StudyPageTop

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #2151

        Participants who were previously receiving JNJ-283 plus daratumumab have the opportunity to continue daratumumab therapy alone. -in the JNJ PD-1 / Dara trial https://www.clinicaltrials.gov/ct2/history/NCT03357952?A=12&B=13&C=merged#StudyPageTop

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #2152

          this Tisotumab Vedotin trial seems cut off? we need to figure out why https://www.clinicaltrials.gov/ct2/history/NCT03245736?A=3&B=4&C=merged#StudyPageTop

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #2153

            A Study Of Daratumumab, Low-Dose Oral Dexamethasone and Cyclophosphamide With Or Without Pomalidomide (DCDP) - fully recruited 120patients , all in Canada https://www.clinicaltrials.gov/ct2/history/NCT03215524?A=7&B=8&C=merged#StudyPageTop

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            • P Offline
              P Offline
              Plimsoller
              wrote on sidst redigeret af
              #2154

              Concerning the TV trial, is the answer not just to send an email to Genmab and ask?

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #2155

                I would not be surpriced if they narrow the targets and downplay TV. I belive they more want to use their money on the hexabody technology.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #2156

                  @Plimsoller not sure it has to be a concern, could be a change in design of the trials or the direction, but i think a good question for Q&A?

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                  • P Offline
                    P Offline
                    peter12
                    wrote on sidst redigeret af
                    #2157

                    De vil bruge 100 mio$ på TV 😉 https://www.nasdaq.com/markets/ipos/company/genmab-as-777502-89779

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #2158

                      @Solsen they have not given any indications for that (yet...) though?

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #2159

                        exactly peter , and it was prominently in their pipeline each time so far.

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                        • P Offline
                          P Offline
                          peter12
                          wrote on sidst redigeret af
                          #2160

                          TV is doing good in bladder but SGEN have a similar drug ?

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                          • Legolas23L Offline
                            Legolas23L Offline
                            Legolas23
                            wrote on sidst redigeret af
                            #2161

                            Hvis der var givet PR på SC, burde så det så ikke være blevet oplyst?

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #2162

                              Nej, det er for tidligt. Cassiopeia blev indsendt 26. marts og fik PR 30. maj. Så 2 mdr er helt normalt.

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                              • B Offline
                                B Offline
                                bikube
                                wrote on sidst redigeret af
                                #2163

                                peter 12 - TV er jo 50/50 samarbejde med Sgen

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #2164

                                  I dont say they will give up TV. Just some indications. Cervix, ovarie and pancreas are interesting. But I dont have a insight in competitive drugs.

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                                  • J Offline
                                    J Offline
                                    Jedi
                                    wrote on sidst redigeret af
                                    #2165

                                    The terminated TV trial - note that it reads “continued treatment with TV” so isn’t it just an offer of continued treatment to responders in the first TV trial? Hence no big deal if it is now shut down

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #2166

                                      Agree, no big deal

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                                      • Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktør
                                        wrote on sidst redigeret af
                                        #2167

                                        Luk i dagens højeste. 🙂

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                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #2168

                                          😄

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