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Genmab — Juli 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • B Offline
    B Offline
    bikube
    wrote on sidst redigeret af
    #2148

    CHMP er positive på Emplicity-Pom-Dex i 3. linie RRMM siger SA.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #2149

      this smoldering SC trial seems fully recruited https://www.clinicaltrials.gov/ct2/history/NCT03301220?A=21&B=22&C=merged#StudyPageTop

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #2150

        Columba reached Primary Completion Date - as expected https://www.clinicaltrials.gov/ct2/history/NCT03277105?A=24&B=25&C=merged#StudyPageTop

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #2151

          Participants who were previously receiving JNJ-283 plus daratumumab have the opportunity to continue daratumumab therapy alone. -in the JNJ PD-1 / Dara trial https://www.clinicaltrials.gov/ct2/history/NCT03357952?A=12&B=13&C=merged#StudyPageTop

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #2152

            this Tisotumab Vedotin trial seems cut off? we need to figure out why https://www.clinicaltrials.gov/ct2/history/NCT03245736?A=3&B=4&C=merged#StudyPageTop

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #2153

              A Study Of Daratumumab, Low-Dose Oral Dexamethasone and Cyclophosphamide With Or Without Pomalidomide (DCDP) - fully recruited 120patients , all in Canada https://www.clinicaltrials.gov/ct2/history/NCT03215524?A=7&B=8&C=merged#StudyPageTop

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              • P Offline
                P Offline
                Plimsoller
                wrote on sidst redigeret af
                #2154

                Concerning the TV trial, is the answer not just to send an email to Genmab and ask?

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #2155

                  I would not be surpriced if they narrow the targets and downplay TV. I belive they more want to use their money on the hexabody technology.

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #2156

                    @Plimsoller not sure it has to be a concern, could be a change in design of the trials or the direction, but i think a good question for Q&A?

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                    • P Offline
                      P Offline
                      peter12
                      wrote on sidst redigeret af
                      #2157

                      De vil bruge 100 mio$ på TV 😉 https://www.nasdaq.com/markets/ipos/company/genmab-as-777502-89779

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #2158

                        @Solsen they have not given any indications for that (yet...) though?

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #2159

                          exactly peter , and it was prominently in their pipeline each time so far.

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                          • P Offline
                            P Offline
                            peter12
                            wrote on sidst redigeret af
                            #2160

                            TV is doing good in bladder but SGEN have a similar drug ?

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                            • Legolas23L Offline
                              Legolas23L Offline
                              Legolas23
                              wrote on sidst redigeret af
                              #2161

                              Hvis der var givet PR på SC, burde så det så ikke være blevet oplyst?

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #2162

                                Nej, det er for tidligt. Cassiopeia blev indsendt 26. marts og fik PR 30. maj. Så 2 mdr er helt normalt.

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                                • B Offline
                                  B Offline
                                  bikube
                                  wrote on sidst redigeret af
                                  #2163

                                  peter 12 - TV er jo 50/50 samarbejde med Sgen

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #2164

                                    I dont say they will give up TV. Just some indications. Cervix, ovarie and pancreas are interesting. But I dont have a insight in competitive drugs.

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                                    • J Offline
                                      J Offline
                                      Jedi
                                      wrote on sidst redigeret af
                                      #2165

                                      The terminated TV trial - note that it reads “continued treatment with TV” so isn’t it just an offer of continued treatment to responders in the first TV trial? Hence no big deal if it is now shut down

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #2166

                                        Agree, no big deal

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                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #2167

                                          Luk i dagens højeste. 🙂

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