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Genmab — Juli 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktør
    wrote on sidst redigeret af
    #2147

    🙂

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    • B Offline
      B Offline
      bikube
      wrote on sidst redigeret af
      #2148

      CHMP er positive på Emplicity-Pom-Dex i 3. linie RRMM siger SA.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #2149

        this smoldering SC trial seems fully recruited https://www.clinicaltrials.gov/ct2/history/NCT03301220?A=21&B=22&C=merged#StudyPageTop

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #2150

          Columba reached Primary Completion Date - as expected https://www.clinicaltrials.gov/ct2/history/NCT03277105?A=24&B=25&C=merged#StudyPageTop

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #2151

            Participants who were previously receiving JNJ-283 plus daratumumab have the opportunity to continue daratumumab therapy alone. -in the JNJ PD-1 / Dara trial https://www.clinicaltrials.gov/ct2/history/NCT03357952?A=12&B=13&C=merged#StudyPageTop

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #2152

              this Tisotumab Vedotin trial seems cut off? we need to figure out why https://www.clinicaltrials.gov/ct2/history/NCT03245736?A=3&B=4&C=merged#StudyPageTop

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #2153

                A Study Of Daratumumab, Low-Dose Oral Dexamethasone and Cyclophosphamide With Or Without Pomalidomide (DCDP) - fully recruited 120patients , all in Canada https://www.clinicaltrials.gov/ct2/history/NCT03215524?A=7&B=8&C=merged#StudyPageTop

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                • P Offline
                  P Offline
                  Plimsoller
                  wrote on sidst redigeret af
                  #2154

                  Concerning the TV trial, is the answer not just to send an email to Genmab and ask?

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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #2155

                    I would not be surpriced if they narrow the targets and downplay TV. I belive they more want to use their money on the hexabody technology.

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #2156

                      @Plimsoller not sure it has to be a concern, could be a change in design of the trials or the direction, but i think a good question for Q&A?

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                      • P Offline
                        P Offline
                        peter12
                        wrote on sidst redigeret af
                        #2157

                        De vil bruge 100 mio$ på TV 😉 https://www.nasdaq.com/markets/ipos/company/genmab-as-777502-89779

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #2158

                          @Solsen they have not given any indications for that (yet...) though?

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #2159

                            exactly peter , and it was prominently in their pipeline each time so far.

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                            • P Offline
                              P Offline
                              peter12
                              wrote on sidst redigeret af
                              #2160

                              TV is doing good in bladder but SGEN have a similar drug ?

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                              • Legolas23L Offline
                                Legolas23L Offline
                                Legolas23
                                wrote on sidst redigeret af
                                #2161

                                Hvis der var givet PR på SC, burde så det så ikke være blevet oplyst?

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #2162

                                  Nej, det er for tidligt. Cassiopeia blev indsendt 26. marts og fik PR 30. maj. Så 2 mdr er helt normalt.

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                                  • B Offline
                                    B Offline
                                    bikube
                                    wrote on sidst redigeret af
                                    #2163

                                    peter 12 - TV er jo 50/50 samarbejde med Sgen

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #2164

                                      I dont say they will give up TV. Just some indications. Cervix, ovarie and pancreas are interesting. But I dont have a insight in competitive drugs.

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                                      • J Offline
                                        J Offline
                                        Jedi
                                        wrote on sidst redigeret af
                                        #2165

                                        The terminated TV trial - note that it reads “continued treatment with TV” so isn’t it just an offer of continued treatment to responders in the first TV trial? Hence no big deal if it is now shut down

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #2166

                                          Agree, no big deal

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                                          0

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