Genmab — Juli 2019

[StockBull]

Hehe sidder nu og øver lidt guitar samtidig med et halvt øje på skærmen og hår samt farve er intakt. Der er lagt købsorder ind på de 1235 og så må vi se.

[Helge_LarsenPI-redaktør]

[bikube]

CHMP er positive på Emplicity-Pom-Dex i 3. linie RRMM siger SA.

[E_L]

this smoldering SC trial seems fully recruited https://www.clinicaltrials.gov/ct2/history/NCT03301220?A=21&B=22&C=merged#StudyPageTop

[E_L]

Columba reached Primary Completion Date - as expected https://www.clinicaltrials.gov/ct2/history/NCT03277105?A=24&B=25&C=merged#StudyPageTop

[E_L]

Participants who were previously receiving JNJ-283 plus daratumumab have the opportunity to continue daratumumab therapy alone. -in the JNJ PD-1 / Dara trial https://www.clinicaltrials.gov/ct2/history/NCT03357952?A=12&B=13&C=merged#StudyPageTop

[E_L]

this Tisotumab Vedotin trial seems cut off? we need to figure out why https://www.clinicaltrials.gov/ct2/history/NCT03245736?A=3&B=4&C=merged#StudyPageTop

[E_L]

A Study Of Daratumumab, Low-Dose Oral Dexamethasone and Cyclophosphamide With Or Without Pomalidomide (DCDP) - fully recruited 120patients , all in Canada https://www.clinicaltrials.gov/ct2/history/NCT03215524?A=7&B=8&C=merged#StudyPageTop

[Plimsoller]

Concerning the TV trial, is the answer not just to send an email to Genmab and ask?

[Solsen]

I would not be surpriced if they narrow the targets and downplay TV. I belive they more want to use their money on the hexabody technology.

[E_L]

@Plimsoller not sure it has to be a concern, could be a change in design of the trials or the direction, but i think a good question for Q&A?

[peter12]

De vil bruge 100 mio$ på TV https://www.nasdaq.com/markets/ipos/company/genmab-as-777502-89779

[E_L]

@Solsen they have not given any indications for that (yet...) though?

[E_L]

exactly peter , and it was prominently in their pipeline each time so far.

[peter12]

TV is doing good in bladder but SGEN have a similar drug ?

[Legolas23]

Hvis der var givet PR på SC, burde så det så ikke være blevet oplyst?

[Bulder]

Nej, det er for tidligt. Cassiopeia blev indsendt 26. marts og fik PR 30. maj. Så 2 mdr er helt normalt.

[bikube]

peter 12 - TV er jo 50/50 samarbejde med Sgen

[Solsen]

I dont say they will give up TV. Just some indications. Cervix, ovarie and pancreas are interesting. But I dont have a insight in competitive drugs.

[Jedi]

The terminated TV trial - note that it reads “continued treatment with TV” so isn’t it just an offer of continued treatment to responders in the first TV trial? Hence no big deal if it is now shut down