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Genmab — December 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #888

    Igen en flot dag hvor der bliver omsat for over 100 mio og Igen, igen lander på et stort rundt nul som det ser ud nu. 😉

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    • V Offline
      V Offline
      Vitus
      wrote on sidst redigeret af
      #889

      Ja og C25 Cap op med 1,38% 🙂

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      • J Offline
        J Offline
        JKY_VH
        wrote on sidst redigeret af
        #890

        Ja bibob, det virker påfaldende tilfældigt:-D

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #891

          Just a moment...

          favicon

          (www.firstwordpharma.com)

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #892

            Gad vide hvorfor så mange sætter spørgsmålstegn til OS ?

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            • T Offline
              T Offline
              Thomas
              wrote on sidst redigeret af
              #893

              Interessant, Sukkeralf. Gad vide hvad det løber op i at købe resultaterne. Jeg har skrevet mig op så jeg får en e-mail når resultaterne løber ind og så kan man købe sig adgang til dem

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #894

                are they worried about actual OS, or that measuring statistically significant OS is impossible due to dara follow-on treatment ?

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #895

                  over ASH we heard ´Importantly, this study did demonstrate that despite the significant improvement with daratumumab in the initial PSF1, it did not impact the response of the patient in the next line of therapy. Therefore, the PSF2 was improved in the daratumumab arm."´

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #896

                    as in this article on Pollux https://www.raredr.com/conferences/ash-2018/nizar-bahlis-md-recaps-followup-trial-showing-combo-therapy-rr-multiple-myeloma-maintains-high-response-rates-

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #897

                      You are right. But why do we still se some uncertainty to that fact.

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #898

                        As I see it, the problem is that you'll never get valid OS comparison between DRd and Rd as pts in the Rd-arm, when they relapse, naturally will prefer DRd (Pollux) to continue with.

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #899

                          Or, if they are refractory to R, then DVd.

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #900

                            seems like a bit of a luxury problem…

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #901

                              Yes but still some KOL questions daras use in first line. To me only price is the question. If its no problem then we se $10 bn without question 🙂

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #902

                                There are doctors with the attitude "save the best for later", who for that reason will not use dara frontline. It's still to be seen how many they are.

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                                • P Offline
                                  P Offline
                                  pauly
                                  wrote on sidst redigeret af
                                  #903

                                  Rimeligt skørt at have den holdning

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #904

                                    yea, that is a job for the JNJ sales force... We had research showing the importance of best treatment first... they will have to push that…

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #905

                                      Certainly a job for JNJ. JW seems confident in winning the battle. 50% instant rise in sales 😉

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                                      • troldmandenT Offline
                                        troldmandenT Offline
                                        troldmanden
                                        wrote on sidst redigeret af
                                        #906

                                        Det har aldrig rigtig givet mening forr mig med det her 50% stigning straks der ligger en godkendelse i 1. line. Hvorffor ikke....? Nu har dde talt om forever at der var stolemangle. Det har været en slags "undskyldning" for væksten ikke har været bedre den seneste tid

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                                        • troldmandenT Offline
                                          troldmandenT Offline
                                          troldmanden
                                          wrote on sidst redigeret af
                                          #907

                                          HVIS det er rigtig vil godkendelse i 1. linee jo iikke løse noget. Så er den ved at ramme et platatueu? Altså at det er SC der skal til for reelt at løfte den meget højere

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