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Genmab — December 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • V Offline
    V Offline
    Vitus
    wrote on sidst redigeret af
    #889

    Ja og C25 Cap op med 1,38% 🙂

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    • J Offline
      J Offline
      JKY_VH
      wrote on sidst redigeret af
      #890

      Ja bibob, det virker påfaldende tilfældigt:-D

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #891

        Just a moment...

        favicon

        (www.firstwordpharma.com)

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #892

          Gad vide hvorfor så mange sætter spørgsmålstegn til OS ?

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          • T Offline
            T Offline
            Thomas
            wrote on sidst redigeret af
            #893

            Interessant, Sukkeralf. Gad vide hvad det løber op i at købe resultaterne. Jeg har skrevet mig op så jeg får en e-mail når resultaterne løber ind og så kan man købe sig adgang til dem

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #894

              are they worried about actual OS, or that measuring statistically significant OS is impossible due to dara follow-on treatment ?

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #895

                over ASH we heard ´Importantly, this study did demonstrate that despite the significant improvement with daratumumab in the initial PSF1, it did not impact the response of the patient in the next line of therapy. Therefore, the PSF2 was improved in the daratumumab arm."´

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #896

                  as in this article on Pollux https://www.raredr.com/conferences/ash-2018/nizar-bahlis-md-recaps-followup-trial-showing-combo-therapy-rr-multiple-myeloma-maintains-high-response-rates-

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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #897

                    You are right. But why do we still se some uncertainty to that fact.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #898

                      As I see it, the problem is that you'll never get valid OS comparison between DRd and Rd as pts in the Rd-arm, when they relapse, naturally will prefer DRd (Pollux) to continue with.

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #899

                        Or, if they are refractory to R, then DVd.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #900

                          seems like a bit of a luxury problem…

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #901

                            Yes but still some KOL questions daras use in first line. To me only price is the question. If its no problem then we se $10 bn without question 🙂

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #902

                              There are doctors with the attitude "save the best for later", who for that reason will not use dara frontline. It's still to be seen how many they are.

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                              • P Offline
                                P Offline
                                pauly
                                wrote on sidst redigeret af
                                #903

                                Rimeligt skørt at have den holdning

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #904

                                  yea, that is a job for the JNJ sales force... We had research showing the importance of best treatment first... they will have to push that…

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #905

                                    Certainly a job for JNJ. JW seems confident in winning the battle. 50% instant rise in sales 😉

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                                    • troldmandenT Offline
                                      troldmandenT Offline
                                      troldmanden
                                      wrote on sidst redigeret af
                                      #906

                                      Det har aldrig rigtig givet mening forr mig med det her 50% stigning straks der ligger en godkendelse i 1. line. Hvorffor ikke....? Nu har dde talt om forever at der var stolemangle. Det har været en slags "undskyldning" for væksten ikke har været bedre den seneste tid

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                                      • troldmandenT Offline
                                        troldmandenT Offline
                                        troldmanden
                                        wrote on sidst redigeret af
                                        #907

                                        HVIS det er rigtig vil godkendelse i 1. linee jo iikke løse noget. Så er den ved at ramme et platatueu? Altså at det er SC der skal til for reelt at løfte den meget højere

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                                        • troldmandenT Offline
                                          troldmandenT Offline
                                          troldmanden
                                          wrote on sidst redigeret af
                                          #908

                                          Det virker llidt som at blæse og haave mel i munden samme tid

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